915572
Pomalidomide-dipiperazine-NH2 hydrochloride
≥95%
Synonym(s):
4-(4-(4-(2-Aminoethyl)piperazine-1-carbonyl)piperazin-1-yl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride, Crosslinker−E3 ligase ligand conjugate, Pomalidomide conjugate, Protein degrader building block for PROTAC® research, Template for synthesis of targeted protein degrader
About This Item
Recommended Products
ligand
pomalidomide
Quality Level
Assay
≥95%
form
powder
reaction suitability
reactivity: carboxyl reactive
reagent type: ligand-linker conjugate
functional group
amine
storage temp.
2-8°C
SMILES string
O=C(N(C1CCC(NC1=O)=O)C2=O)C3=C2C=CC=C3N4CCN(C(N5CCN(CCN)CC5)=O)CC4
1 of 4
This Item | 901830 | 901832 | 920738 |
---|---|---|---|
amine | - | amine | amine |
reactivity: carboxyl reactive, reagent type: ligand-linker conjugate | - | reactivity: carboxyl reactive, reagent type: ligand-linker conjugate | reactivity: carboxyl reactive, reagent type: ligand-linker conjugate |
100 | - | - | 100 |
2-8°C | 2-8°C | 2-8°C | −20°C |
powder | powder or crystals | powder | crystals |
Application
Other Notes
Portal: Building PROTAC® Degraders for Targeted Protein Degradation
Targeted Protein Degradation by Small Molecules
Small-Molecule PROTACS: New Approaches to Protein Degradation
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Legal Information
related product
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Articles
Protein Degrader Building Blocks are a collection of crosslinker-E3 ligand conjugates with a pendant functional group for covalent linkage to a target ligand.
Protein Degrader Building Blocks are a collection of crosslinker-E3 ligand conjugates with a pendant functional group for covalent linkage to a target ligand.
Protein Degrader Building Blocks are a collection of crosslinker-E3 ligand conjugates with a pendant functional group for covalent linkage to a target ligand.
Protein Degrader Building Blocks are a collection of crosslinker-E3 ligand conjugates with a pendant functional group for covalent linkage to a target ligand.
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