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769827

Sigma-Aldrich

Resomer® RG 752 S, Poly(D,L-lactide-co-glycolide)

ester terminated, lactide:glycolide 75:25

Synonym(s):

Resomer® RG 752 S, PLGA

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About This Item

Linear Formula:
HO[C2H4O2]n[C2H2O2]mCH3
CAS Number:
UNSPSC Code:
12162002
NACRES:
NA.23

Quality Level

form

amorphous

feed ratio

lactide:glycolide 75:25

viscosity

0.16-0.24 dL/g

transition temp

Tg 44-50 °C

storage temp.

2-8°C

Application

Resomer® RG 752 S, Poly(D,L-lactide-co-glycolide), a biodegradable and biocompatible aliphatic polyester, can be used in the development of nano and microparticles. It is a pharmaceutical polymer for potential usage in drug delivery and gene delivery. It forms a three-dimensional porous scaffold, which can be used in tissue engineering.

Legal Information

RESOMER is a registered trademark of Evonik Rohm GmbH

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Development and evaluation of novel biodegradable microspheres based on poly (d, l-lactide-co-glycolide) and poly (varepsilon-caprolactone) for controlled delivery of doxycycline in the treatment of human periodontal pocket: in vitro and in vivo studies
Mundargi RC, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 119(1), 59-68 (2007)
In vitro degradation of three-dimensional porous poly (D, L-lactide-co-glycolide) scaffolds for tissue engineering
Wu L and Ding J
Biomaterials, 25(27), 5821-5830 (2004)
Nanoparticles made of fluorescence-labelled poly (L-lactide-co-glycolide): preparation, stability, and biocompatibility
Weiss B, et al.
Journal of Nanoscience and Nanotechnology, 6(9-10), 3048-3056 (2006)
Nano/micro technologies for delivering macromolecular therapeutics using poly (D, L-lactide-co-glycolide) and its derivatives
Mundargi RC, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 125(3), 193-209 (2008)

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