549223

3,4-Difluorothiophenol

96%

• Linear Formula: F₂C₆H₃SH
• CAS Number: 60811-24-7
• Molecular Weight: 146.16
• MDL number: MFCD03094279
• UNSPSC Code: 12352100
• PubChem Substance ID: 24879070
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 96%
• refractive index: n20/D 1.528 (lit.)
• bp: 169-170 °C (lit.)
• density: 1.323 g/mL at 25 °C (lit.)
• SMILES string: Fc1ccc(S)cc1F
• InChI: 1S/C6H4F2S/c7-5-2-1-4(9)3-6(5)8/h1-3,9H
• InChI key: BGVRHDQMTMPAEZ-UHFFFAOYSA-N

Description

General description

3,4-Difluorothiophenol is a halo-substituted thiol derivative.

Application

3,4-Difluorothiophenol may be used:

• To prepare a novel 3,4-difluorophenylthiomethyl group containing phthalazine derivative, which shows high cytotoxic activity.
• To prepare a fluorothiophenyl modified poly(vinyl chloride) membrane with improved gas permeability efficiency.
• As a ligand to synthesize noble metal quantum clusters (QCs).
• To prepare ethyl 5-(aminosulfonyl)-2-[(3,4-difluorophenyl)thio]nicotinate, an intermediate for preparing potent thioether benzenesulfonamide inhibitors of carbonic anhydrases II and IV.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Warning
• Hazard Statements: H226,H315,H319,H335
• Precautionary Statements: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 120.0 °F - closed cup
• Flash Point(C): 48.9 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves