533068
6-Methoxy-3-pyridinecarboxaldehyde
98%
Synonym(s):
6-Methoxy-3-nicotinaldehyde
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About This Item
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Assay
98%
mp
51-54 °C (lit.)
functional group
aldehyde
SMILES string
COc1ccc(C=O)cn1
InChI
1S/C7H7NO2/c1-10-7-3-2-6(5-9)4-8-7/h2-5H,1H3
InChI key
CTAIEPPAOULMFY-UHFFFAOYSA-N
General description
6-Methoxy-3-pyridinecarboxaldehyde, also known as 6-methoxy-3-nicotinaldehyde, can be prepared from 5-bromo-2-methoxypyridine.
Application
6-Methoxy-3-pyridinecarboxaldehyde may be used to prepare 6-methoxy-4-methyl-3-pyridinecarboxaldehyde and 6-methoxy-5-methyl-3-pyridinecarboxaldehyde.
An intermediate for the synthesis of the somatostatic sst3 receptor.
Substrate used in a synthesis of flavanones via an L-proline-catalyzed condensation with o-hydroxyarylketones.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Lithiation of methoxypyridines directed by ?-amino alkoxides.
The Journal of Organic Chemistry, 55(1), 69-73 (1990)
Tetrahedron Letters, 46, 6991-6991 (2005)
Tetrahedron Asymmetry, 14, 3469-3477 (2003)
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