52270

1-Hexadecanethiol

≥95.0% (GC)

• Synonym(s): Cetyl mercaptan, Hexadecyl mercaptan, Mercaptan C₁₆
• Linear Formula: CH₃(CH₂)₁₅SH
• CAS Number: 2917-26-2
• Molecular Weight: 258.51
• Beilstein: 1748495
• EC Number: 220-846-6
• MDL number: MFCD00011677
• UNSPSC Code: 12352100
• PubChem Substance ID: 57651351
• NACRES: NA.22

Properties

• Assay: ≥95.0% (GC)
• refractive index: n20/D 1.462 (lit.); n20/D 1.464
• bp: 184-191 °C/7 mmHg (lit.)
• mp: 18-20 °C (lit.)
• transition temp: solidification point 15-18 °C(lit.)
• density: 0.84 g/mL at 25 °C (lit.)
• functional group: thiol
• SMILES string: CCCCCCCCCCCCCCCCS
• InChI: 1S/C16H34S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h17H,2-16H2,1H3
• InChI key: ORTRWBYBJVGVQC-UHFFFAOYSA-N

Description

General description

1-Hexadecanethiol (HDT) readily forms self-assembled monolayer (SAMs) on gold surfaces. Phase separation characteristics of binary SAMs [made up of HDT and 3-mercaptopropionic acid] on the surface of Au(111) have been investigated. Interaction between gold surface and SAM of HDT has been investigated by atomic force microscopy (AFM).

Application

1-Hexadecanethiol has been used in the preparation of cholesterol-PIE12-trimer and alkyl-PIE12-trimer (PIE12-trimer = protease-resistant trimeric D-peptide inhibitor). It may be used for the functionalization of silver nanowires.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 215.6 °F - closed cup
• Flash Point(C): 102 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves