439053

(+)-Isopulegol

99%

• Synonym(s): (1S,2R,5S)-2-Isopropenyl-5-methylcyclohexanol, (1S,3S,4R)-p-Menth-8-en-3-ol
• Empirical Formula (Hill Notation): C₁₀H₁₈O
• CAS Number: 104870-56-6
• Molecular Weight: 154.25
• Beilstein: 4659691
• MDL number: MFCD00213790
• UNSPSC Code: 12352002
• PubChem Substance ID: 24867322
• NACRES: NA.22

Properties

• Assay: 99%
• form: liquid
• optical activity: [α]20/D +22°, neat
• refractive index: n20/D 1.469 (lit.)
• bp: 91 °C/12 mmHg (lit.)
• density: 0.912 g/mL at 25 °C (lit.)
• functional group: hydroxyl
• SMILES string: C[C@H]1CC[C@@H]([C@@H](O)C1)C(C)=C
• InChI: 1S/C10H18O/c1-7(2)9-5-4-8(3)6-10(9)11/h8-11H,1,4-6H2,2-3H3/t8-,9+,10-/m0/s1
• InChI key: ZYTMANIQRDEHIO-AEJSXWLSSA-N

Description

General description

Isopulegol is a monoterpene alcohol, which is generally found in essential oils of various plants. It is widely used as a fragrance ingredient in cosmetics, shampoos and toilet soaps. Isopulegol is also a key intermediate in the synthesis of (−)-menthol.

Application

(+)-Isopulegol can be used as a starting material to synthesize:

• A natural product (−)-isopiperitenone.
• Medicinally important octahydro-2H-chromen-4-ol derivatives by reacting with benzaldehydes.
• Antituberculosis diterpenoid named 12-epi-ileabethoxazole.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 172.4 °F - closed cup
• Flash Point(C): 78 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves