393835

o-Xylylene N,N-diethylphosphoramidite

technical grade

• Synonym(s): 3-(Diethylamino)-1,5-dihydro-2,4,3-benzodioxaphosphepine
• Empirical Formula (Hill Notation): C₁₂H₁₈NO₂P
• CAS Number: 82372-35-8
• Molecular Weight: 239.25
• Beilstein: 3590087
• MDL number: MFCD00192025
• UNSPSC Code: 12352100
• PubChem Substance ID: 24864545
• NACRES: NA.22

Properties

• grade: technical grade
• form: liquid
• refractive index: n20/D 1.541 (lit.)
• bp: 95-96 °C/0.1 mmHg (lit.)
• solubility: THF: soluble; acetonitrile: soluble; cold water: insoluble; dichloromethane: soluble
• density: 1.109 g/mL at 25 °C (lit.)
• functional group: amine
• SMILES string: CCN(CC)P1OCc2ccccc2CO1
• InChI: 1S/C12H18NO2P/c1-3-13(4-2)16-14-9-11-7-5-6-8-12(11)10-15-16/h5-8H,3-4,9-10H2,1-2H3
• InChI key: JDAKPBBWYIWXJF-UHFFFAOYSA-N

Description

Application

o-Xylylene N,N-diethylphosphoramidite (N,N-diethyl-1,5-dihydro-2,4,3-benzodioxaphosphepin-3-amine) may be used in the synthesis of the following:

• bicyclic glycosyl phosphite
• pentakis(o-xylylene phosphate)
• o-xylylene alkyl phosphites

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 188.6 °F - closed cup
• Flash Point(C): 87 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves