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291102

Sigma-Aldrich

Piperonylbutoxide

technical grade, 90%

Synonym(s):

2-(2-Butoxyethoxy)ethyl (6-propylpiperonyl) ether, 4,5-Methylenedioxy-2-propylbenzyldiethyleneglycol butyl ether

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About This Item

Empirical Formula (Hill Notation):
C19H30O5
CAS Number:
51-03-6
Molecular Weight:
338.44
Beilstein:
288063
EC Number:
200-076-7
MDL number:
MFCD00005842
UNSPSC Code:
12352100
PubChem Substance ID:
24857511
NACRES:
NA.22

grade

technical grade

Assay

90%

refractive index

n20/D 1.498 (lit.)

bp

155 °C/0.3 mmHg (lit.)

solubility

water: slightly soluble 0.0289 g/L at 20.4 °C

density

1.059 g/mL at 25 °C (lit.)

functional group

ether

SMILES string

CCCCOCCOCCOCc1cc2OCOc2cc1CCC

InChI

1S/C19H30O5/c1-3-5-7-20-8-9-21-10-11-22-14-17-13-19-18(23-15-24-19)12-16(17)6-4-2/h12-13H,3-11,14-15H2,1-2H3

InChI key

FIPWRIJSWJWJAI-UHFFFAOYSA-N

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General description

Piperonylbutoxide is a safe insecticide for household and field. Effect of piperonyl butoxide, a synthetic methylenedioxyphenyl inhibitor of cytochrome(s) P450, on the toxicity of organophosphate insecticides to cladoceran test species (Ceriodaphnia dubia, Daphnia magna and Daphnia pulex) has been investigated.

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H319,H335,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH066

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

339.8 °F - closed cup

Flash Point(C)

171 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Piperonyl butoxide, a new and safe insecticide for the household and field.
W E DOVE
Pests and their control, 15(9), 30-30 (1947-09-01)
G T Ankley et al.
Ecotoxicology and environmental safety, 21(3), 266-274 (1991-06-01)
Experiments were conducted to determine the effects of piperonyl butoxide, a synthetic methylenedioxyphenyl inhibitor of cytochrome(s) P450, on the toxicity of organophosphate insecticides to three cladoceran test species: Ceriodaphnia dubia. Daphnia magna, and Daphnia pulex. Coadministration of piperonyl butoxide effectively
Olivier J T Briët et al.
Malaria journal, 12, 77-77 (2013-02-28)
The effectiveness of insecticide-treated nets in preventing malaria is threatened by developing resistance against pyrethroids. Little is known about how strongly this affects the effectiveness of vector control programmes. Data from experimental hut studies on the effects of long-lasting, insecticidal
Rodolphe Poupardin et al.
PLoS neglected tropical diseases, 8(3), e2743-e2743 (2014-03-22)
Thailand is currently experiencing one of its worst dengue outbreaks in decades. As in most countries where this disease is endemic, dengue control in Thailand is largely reliant on the use of insecticides targeting both immature and adult stages of
Despina Philippou et al.
Pest management science, 69(4), 499-506 (2012-09-13)
It has been reported previously that piperonyl butoxide (PBO) can inhibit both P450 and esterase activity. Although the method by which PBO combines with cytochrome P450 has been identified, the way in which it acts as an esterase inhibitor has
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