253596
16-DOXYL-stearic acid, free radical
Synonym(s):
16-SASL, 16DOXYL, 16NS, 2-(14-Carboxytetradecyl)-2-ethyl-4,4-dimethyl-3-oxazolidinyloxy, free radical
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About This Item
Empirical Formula (Hill Notation):
C22H42NO4
CAS Number:
Molecular Weight:
384.57
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
form
solid
mp
47-55 °C (lit.)
functional group
carboxylic acid
ether
storage temp.
2-8°C
SMILES string
CCC1(CCCCCCCCCCCCCCC(O)=O)OCC(C)(C)N1[O]
InChI
1S/C22H42NO4/c1-4-22(23(26)21(2,3)19-27-22)18-16-14-12-10-8-6-5-7-9-11-13-15-17-20(24)25/h4-19H2,1-3H3,(H,24,25)
InChI key
RPAZYIOIDZRJOO-UHFFFAOYSA-N
Application
Involved in membrane studies including:
- Dynamics and state of lipid bilayer-internal water using 1H dynamic nuclear polarization
- Distribution of fatty acids
- Transversal relaxation of nitroxides for PELDOR Spectroscopy
- Effects of different lipid components on detergent-resistant membranes
Spin label for membrane fluidity studies.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
235.4 °F - closed cup
Flash Point(C)
113 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Gábor Balogh et al.
PloS one, 6(6), e21182-e21182 (2011-06-24)
Cellular membranes respond rapidly to various environmental perturbations. Previously we showed that modulations in membrane fluidity achieved by heat stress (HS) resulted in pronounced membrane organization alterations which could be intimately linked to the expression and cellular distribution of heat
M A Baqué et al.
Biochemical and biophysical research communications, 505(4), 1038-1042 (2018-10-13)
Different spin labels were incorporated to the membranes of cultured insect UFL-AG-286 cells in order to characterize their physical properties by Electron Paramagnetic Resonance spectroscopy (EPR). The spectrum of the spin label 12-SASL incorporated to cell membranes was similar as those
X Qi et al.
Circulation, 104(13), 1544-1549 (2001-09-26)
The maintenance and termination of reentry arrhythmias are determined by tissue properties such as refractoriness and conduction velocity. Although the effects of Na(+) and K(+) channel block on electrophysiological properties and defibrillation threshold (DFT) have been studied, little is known
N Rapoport et al.
Archives of biochemistry and biophysics, 384(1), 100-108 (2001-01-09)
To assess the effect of a polymeric surfactant, Pluronic P-105 on the activity of electron transport chains in the mitochondria of HL-60 cells, the bioreduction rates of two membrane-localized lipophilic spin probes, 16-doxylstearic acid methyl ester (16-DSME) and 5-doxylstearic acid
Matthias J N Junk et al.
Biophysical journal, 100(9), 2293-2301 (2011-05-05)
The structure of human serum albumin loaded with a metal porphyrin and fatty acids in solution is characterized by orientation-selective double electron-electron resonance (DEER) spectroscopy. Human serum albumin, spin-labeled fatty acids, and Cu(II) protoporphyrin IX-a hemin analog-form a fully self-assembled
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