205354

(Chloromethyl)trimethylsilane

98%

• Synonym(s): (Trimethylsilyl)methyl chloride
• Linear Formula: (CH₃)₃SiCH₂Cl
• CAS Number: 2344-80-1
• Molecular Weight: 122.67
• Beilstein: 906705
• EC Number: 219-058-5
• MDL number: MFCD00000878
• UNSPSC Code: 12352103
• PubChem Substance ID: 24852326
• NACRES: NA.22

Properties

• vapor pressure: ~25 mmHg ( 20 °C)
• Quality Level: 100
• Assay: 98%
• form: liquid
• refractive index: n20/D 1.418 (lit.)
• bp: 98-99 °C (lit.)
• density: 0.879 g/mL at 25 °C (lit.)
• SMILES string: C[Si](C)(C)CCl
• InChI: 1S/C4H11ClSi/c1-6(2,3)4-5/h4H2,1-3H3
• InChI key: OOCUOKHIVGWCTJ-UHFFFAOYSA-N

Description

Application

(Chloromethyl)trimethylsilane can be treated with aldehydes or ketones in the presence of triphenylphosphine to synthesize terminal alkenes. It can also be used in the preparation of a reagent, trimethylsilylmethyl magnesium chloride, commonly used in Peterson methylenation.

Packaging

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H315,H319,H335
• Precautionary Statements: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 24.8 °F - closed cup
• Flash Point(C): -4 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves