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143936

Sigma-Aldrich

Propionamide

97%

Synonym(s):

Propanamide, Propylamide

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About This Item

Linear Formula:
CH3CH2CONH2
CAS Number:
79-05-0
Molecular Weight:
73.09
EC Number:
201-172-1
MDL number:
MFCD00008039
UNSPSC Code:
12352100
PubChem Substance ID:
24848618
NACRES:
NA.22

Assay

97%

bp

213 °C (lit.)

mp

76-79 °C (lit.)

solubility

alcohol: freely soluble
chloroform: freely soluble
diethyl ether: freely soluble
water: freely soluble

density

1.042 g/mL at 25 °C (lit.)

functional group

amide

SMILES string

CCC(N)=O

InChI

1S/C3H7NO/c1-2-3(4)5/h2H2,1H3,(H2,4,5)

InChI key

QLNJFJADRCOGBJ-UHFFFAOYSA-N

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General description

Propionamide on γ-irradiation reacts with sulfur dioxide and this reaction has been studied by ESR spectroscopy, gas absorption measurements and X-ray diffraction.

Application

Propionamide was used as adsorbent in the determination of adsorption isotherms of acetamide and propionamide on multi-wall carbon nanotube. It was used in a robust screening method to study biotransformations using (+)-γ-lactamase enzyme.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000391695
0000360373
0000361664
0000391695
0000361664

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Study of Adsorption Isotherms of Acetamide and Propionamide on Carbon Nanotube.
Vadi M and Moradi N.
Orient. J. Chem., 27(4), 1491-1491 (2011)
Reactions of Gases with Irradiated Organic Solids: III. Reactions of Propionamide, n-Butyramide, Isobutyramide, Methacrylamide, Valeramide, and Stearamide with Sulfur Dioxide.
Perotti A, et al.
Mol. Cryst. Liq. Cryst., 9(1), 323-342 (2969)
David Crich et al.
The Journal of organic chemistry, 74(9), 3389-3393 (2009-04-25)
Beta-thiolactones monosubstituted in the 3-position by alkyl and carbamoyl groups undergo nucleophilic ring opening by arenethiolates through a process involving an S(N)2-type attack at the 4-position leading to 3-arylthiopropionates substituted in the 2-position. These thiocarboxylates can be trapped in situ
Nobuhito Yukuhiro et al.
Brain research, 1027(1-2), 59-66 (2004-10-21)
We investigated the effects of (S)-N-[2-(1,6,7,8-tetrahydro-2H-indeno-[5,4]furan-8-yl)ethyl]propionamide (ramelteon, TAK-375), a novel MT1/MT2 receptor agonist, on nocturnal sleep in freely moving monkeys and compared these results with those of melatonin and zolpidem. Treatment with ramelteon (0.03 and 0.3 mg/kg, p.o.) significantly shortened
Ruth Oltenfreiter et al.
Nuclear medicine and biology, 31(4), 459-468 (2004-04-20)
Several studies have demonstrated a positive correlation between tumor progression and expression of extracellular proteinases such as matrix metalloproteinases (MMPs). MMP-2 and MMP-9 have become attractive targets for cancer research because of their increased expression in human malignant tumor tissues
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