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112305

Sigma-Aldrich

Ethyl propionate

99%

Synonym(s):

Ethyl propanoate, Propionic acid ethyl ester

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About This Item

Linear Formula:
CH3CH2COOC2H5
CAS Number:
105-37-3
Molecular Weight:
102.13
Beilstein:
506287
EC Number:
203-291-4
MDL number:
MFCD00009308
UNSPSC Code:
12352100
eCl@ss:
39022258
PubChem Substance ID:
24847086
NACRES:
NA.22

vapor density

3.52 (vs air)

Quality Level

100

vapor pressure

40 mmHg ( 27.2 °C)

Assay

99%

form

liquid

autoignition temp.

887 °F

expl. lim.

11 %

refractive index

n20/D 1.384 (lit.)

bp

99 °C (lit.)

mp

−73 °C (lit.)

density

0.888 g/mL at 25 °C (lit.)

functional group

ester

SMILES string

CCOC(=O)CC

InChI

1S/C5H10O2/c1-3-5(6)7-4-2/h3-4H2,1-2H3

InChI key

FKRCODPIKNYEAC-UHFFFAOYSA-N

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General description

Ethyl propionate is a model for studying the fatty acid ethyl esters which are used as first-generation biodiesel.

Application

Ethyl propionate was used to study the effect of its gavage administration on gastric toxicity in male F344 rats.
Ethyl propionate, when used for contact dissolution of cholesterol gallstones, shows reduced side effects (attributable to increased blood levels) in piglets when compared to methyl tert-butyl ether.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

53.6 °F - closed cup

Flash Point(C)

12 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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B I Ghanayem et al.
Toxicology and applied pharmacology, 80(2), 336-344 (1985-09-15)
Earlier studies conducted in this laboratory demonstrated that gavage administration of ethyl acrylate caused pronounced gastric toxicity in rats given single or repeated doses. The current studies were undertaken to investigate the structural, metabolic, and physical basis of this chemically
Vibeke F Andersen et al.
The journal of physical chemistry. A, 116(21), 5164-5179 (2012-04-25)
Ethyl propionate is a model for fatty acid ethyl esters used as first-generation biodiesel. The atmospheric chemistry of ethyl propionate was investigated at 980 mbar total pressure. Relative rate measurements in 980 mbar N(2) at 293 ± 0.5 K were
Inmaculada Romero et al.
Journal of agricultural and food chemistry, 65(21), 4314-4320 (2017-05-11)
Freeze injuries in olives are responsible for the 'frostbitten olives' sensory defect that is sometimes detected in virgin olive oil. This defect is becoming one of the most common negative attributes today because climate change has modified weather patterns. The
O Esch et al.
Hepatology (Baltimore, Md.), 18(2), 373-379 (1993-08-01)
We performed experiments in anesthetized piglets with two cholesterol gallstone solvents, methyl tert-butyl ether and ethyl propionate, to determine whether blood levels of either solvent would increase during gallbladder instillation of these solvents under conditions simulating gallstone dissolution. The solvent
O Esch et al.
Hepatology (Baltimore, Md.), 16(4), 984-991 (1992-10-01)
Experiments were performed in anesthetized rabbits and piglets to assess gallbladder mucosal injury during irrigation with methyl tert-butyl ether, a C5 ether, or ethyl propionate, a C5 ester--two organic solvents used in the contact dissolution of cholesterol gallstones. In 44
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