Skip to Content
Merck
All Photos(1)

Key Documents

RAB0797

Sigma-Aldrich

Mouse IgA ELISA Kit

Synonym(s):

IgA, Immunoglobulin A

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

mouse

technique(s)

ELISA: suitable

assay range

inter-assay cv: <10%
intra-assay cv: <12%

shipped in

wet ice

storage temp.

−20°C

General description

The antibody pair provided in this kit recognizes Mouse IgA.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Immunoglobulin A (IgA) is majorly found in the mucosal secretions. IgA exists as two subclasses, IgA1 and IgA2. IgA is a dimer in animals, but a monomer in humans. IgA interacts with the Fc fragment of IgA receptor (FCAR) to elicit immune response against inhaled pathogens. Secretory IgA (S-IgA) produced by B1 lymphocytes triggers phagocytosis and leucocyte respiratory burst. S-IgA exists as a polymer and is crucial for primary defense. The high levels of IgA in human milk and colostrum may provide immune protection to infants. Deficiency of IgA leads to increased susceptibility to infections. High levels of IgA in kidney is present in IgA nephropathy and IgA myeloma. Autoantibodies of IgA is present in celiac disease.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Shun He et al.
Nature, 566(7742), 115-119 (2019-02-01)
The biochemical response to food intake must be precisely regulated. Because ingested sugars and fats can feed into many anabolic and catabolic pathways1, how our bodies handle nutrients depends on strategically positioned metabolic sensors that link the intrinsic nutritional value
Anna-Carin Lundell et al.
Scientific reports, 7(1), 15503-15503 (2017-11-16)
Boys present with higher proportions of immature/naïve CD5
Chise Suzuki et al.
PloS one, 12(12), e0188985-e0188985 (2017-12-09)
The molecular mechanisms of strain-specific probiotic effects and the impact of the oral administration of probiotic strains on the host's gene expression are not yet well understood. The aim of this study was to investigate the strain-specific effects of probiotic
IgA function-variations on a theme
Woof, Jenny M and Kerr, Michael A
Immunology, 113(2), 175-177 (2004)
Isabelle Zenklusen et al.
The Journal of infectious diseases, 217(10), 1569-1578 (2018-02-14)
The assessment of antibody responses after immunization with radiation-attenuated, aseptic, purified, cryopreserved Plasmodium falciparum sporozoites (Sanaria PfSPZ Vaccine) has focused on IgG isotype antibodies. Here, we aimed to investigate if P. falciparum sporozoite binding and invasion-inhibitory IgM antibodies are induced

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service