NP9
TERGITOL™
Type NP-9
Synonym(s):
Mono(p-nonylphenyl)ether, Nonoxynol-9, Polyethylene glycol mono(branched p-nonylphenyl) ether
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About This Item
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biological source
(chemical)
description
non-ionic
type
Type NP-9
form
liquid
mol wt
616 g/mol
CMC
60 ppm
transition temp
cloud point 54 °C
solubility
water: soluble
HLB
12.9
SMILES string
CCCCCCCCCC1=CC=C(C=C1)OCCO
InChI
1S/C17H28O2/c1-2-3-4-5-6-7-8-9-16-10-12-17(13-11-16)19-15-14-18/h10-13,18H,2-9,14-15H2,1H3
InChI key
KUXGUCNZFCVULO-UHFFFAOYSA-N
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General description
Tergitol NP 9 is a versatile nonionic surfactant that finds applications in cell biology, biochemical, and formulation research. Its unique properties, arising from its hydrophilic and hydrophobic components, make it an effective wetting agent, emulsifier, dispersant, and detergent.
In protein research, Tergitol plays a crucial role in facilitating protein analysis and purification. Its detergent properties enable it to lyse cells, releasing soluble proteins, and solubilizing membrane proteins and lipids, making them accessible for further study. Additionally, it may also be employed in protein crystallization, preventing non-specific binding during affinity purification and immunoassay procedures, and serves as an additive in electrophoresis. Tergitol, extending beyond protein research, finds versatile applications in various industries, serving as a valuable component in formulation research due to its ability to emulsify, disperse, and solubilize, thereby enhancing the stability and homogeneity of different mixtures.
Surfactants, possessing both hydrophilic and hydrophobic components, fall into two main categories: ionic, which ionize in water (anionic, cationic, or ampholytic), and nonionic, which do not ionize. Tergitol NP 9 product is a nonionic surfactant with diverse applications such as emulsification, dispersion, solubilization, and detergent use.
In protein research, Tergitol plays a crucial role in facilitating protein analysis and purification. Its detergent properties enable it to lyse cells, releasing soluble proteins, and solubilizing membrane proteins and lipids, making them accessible for further study. Additionally, it may also be employed in protein crystallization, preventing non-specific binding during affinity purification and immunoassay procedures, and serves as an additive in electrophoresis. Tergitol, extending beyond protein research, finds versatile applications in various industries, serving as a valuable component in formulation research due to its ability to emulsify, disperse, and solubilize, thereby enhancing the stability and homogeneity of different mixtures.
Surfactants, possessing both hydrophilic and hydrophobic components, fall into two main categories: ionic, which ionize in water (anionic, cationic, or ampholytic), and nonionic, which do not ionize. Tergitol NP 9 product is a nonionic surfactant with diverse applications such as emulsification, dispersion, solubilization, and detergent use.
Application
TERGITOL™ has been used in cytotoxicity assays to treat Vero cells for producing cytotoxic (100% dead) controls. It may be used in paper & textile processing, laundry, dust control, agrochemicals, metalworking fluids and paints & coatings.
Tergitol has been used in a study to assess a method to determine nickel using ultrasonic-assisted cloud point extraction. It has also been used in a study to investigate a method for the detection of Salmonella Enteritidis via an Enteritidis-specific real time PCR assay
Features and Benefits
- Excellent detergent quality
- Outstanding wetting
- Flexible solubility characteristics
- Unique handling properties
- Low odor
- Can be rinsed easily
- Chemically stable in the presence of dilute acids, bases, and salts
- Compatible with organic solvents, soaps, anionic, and other nonionic surfactants
Other Notes
Polyglycol ether (nonionic) surfactants.
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Legal Information
TERGITOL is a trademark of The Dow Chemical Company ("Dow") or an affiliated company of Dow
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Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
476.6 °F - closed cup
Flash Point(C)
247 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Listings
Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.
EU REACH SVHC Candidate List
CAS No.
EU REACH Annex XVII (Restriction List)
CAS No.
EU REACH Annex XIV (Authorisation List)
CAS No.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Adriana Pliego Zamora et al.
Virology, 495, 18-32 (2016-05-07)
West Nile Virus (WNV) is a mosquito-borne flavivirus that can cause neuroinvasive disease in humans and animals for which no therapies are currently available. We studied an established combination of monoterpene alcohols (CMA) derived from Melaleuca alternifolia, against WNV infection.
Ana De la Parra-Guerra et al.
Ecotoxicology and environmental safety, 197, 110588-110588 (2020-04-15)
The ethoxylated isomers of nonylphenol (NPEs, NP-9) are one of the main active ingredients present in nonionic surfactants employed as herbicides, cosmetics, paints, plastics, disinfectants and detergents. These chemicals and their metabolites are commonly found in environmental matrices. The aim
Maryam Seyedmajidi et al.
Biomedical materials (Bristol, England), 13(2), 025015-025015 (2017-11-15)
Bone defects are common and persistent problems in clinical orthopedics and dentistry. The development of synthetic reconstruction materials is essential owing to the restricted access to natural bone grafts, disease transmission risks, surgical costs, donor-site morbidity, infections, and immune response-related
Emily S Savela et al.
PLoS biology, 18(3), e3000651-e3000651 (2020-03-20)
Rapid antibiotic susceptibility testing (AST) for Neisseria gonorrhoeae (Ng) is critically needed to counter widespread antibiotic resistance. Detection of nucleic acids in genotypic AST can be rapid, but it has not been successful for β-lactams (the largest antibiotic class used
Bwalya Lungu et al.
Journal of food protection, 75(4), 743-747 (2012-04-11)
Conventional culture methods have traditionally been considered the "gold standard" for the isolation and identification of foodborne bacterial pathogens. However, culture methods are labor-intensive and time-consuming. A Salmonella enterica serotype Enteritidis-specific real-time PCR assay that recently received interim approval by
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