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M2946

Sigma-Aldrich

Mosapride citrate salt dihydrate

≥98% (HPLC), solid, 5-HT₄ receptor agonist

Synonym(s):

4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl ]-2-morpholinyl]methyl]benzamide citrate dihydrate

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About This Item

Empirical Formula (Hill Notation):
C21H25ClFN3O3 · C6H8O7 · 2H2O
CAS Number:
Molecular Weight:
650.05
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

product name

Mosapride citrate salt dihydrate,

Assay

≥98% (HPLC)

Quality Level

form

solid

solubility

DMSO: ≥5 mg/mL

originator

Takeda

storage temp.

2-8°C

SMILES string

O.O.OC(=O)CC(O)(CC(O)=O)C(O)=O.CCOc1cc(N)c(Cl)cc1C(=O)NCC2CN(CCO2)Cc3ccc(F)cc3

InChI

1S/C21H25ClFN3O3.C6H8O7.2H2O/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14;7-3(8)1-6(13,5(11)12)2-4(9)10;;/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);2*1H2

InChI key

KVKIQHMTGSGTFO-UHFFFAOYSA-N

Biochem/physiol Actions

Mosapride is found effective against chronic gastritis, functional dyspepsia and gastro-oesophageal reflux disease. It is useful in treating many other symptoms associated with gastrointestinal disorders. Mosapride is known to improve digestive motility.
5-HT4 receptor agonist and 5-HT3 receptor antagonist

Features and Benefits

This compound was developed by Takeda. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mosapride
Curran MP and Robinson DM
Drugs, 68(7), 981-991 (2008)

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