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H1758

Sigma-Aldrich

Hydrochloric acid

36.5-38.0%, BioReagent, for molecular biology

Synonym(s):

HCL, Hydrogen Chloride Solution, Muriatic Acid

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About This Item

Empirical Formula (Hill Notation):
HCl
CAS Number:
7647-01-0
Molecular Weight:
36.46
Beilstein:
1098214
EC Number:
231-595-7
MDL number:
MFCD00011324
UNSPSC Code:
12352301
PubChem Substance ID:
24895478
NACRES:
NA.31
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grade

for molecular biology

Quality Level

200

vapor density

1.3 (vs air)

vapor pressure

3.23 psi ( 21.1 °C)
7.93 psi ( 37.7 °C)

product line

BioReagent

Assay

36.5-38.0%

form

liquid

concentration

30-50%

color

light yellow

pH

<1 (20 °C)

bp

>100 °C (lit.)

solubility

H2O: soluble

density

1.070 g/cm3 at 20 °C (lit.)

cation traces

Fe: ≤0.2 ppm
heavy metals (as Pb): ≤1 ppm

suitability

suitable for molecular biology

SMILES string

Cl

InChI

1S/ClH/h1H

InChI key

VEXZGXHMUGYJMC-UHFFFAOYSA-N

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Application

Hydrochloric acid has been used:
  • for the solubilization of formazan crystals[1]
  • to adjust pH in various buffers[2][3]
  • for the preparation of giant reed extract[4]

Hydrochloric acid has been used:
  • in cell viability assays[5]
  • for DNA denaturation[6]
  • for pH adjustments in sucrose hydrolysis experiment[7]

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H290,H314,H335

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW6636
MKCS9054
MKCS8724
MKCT7075
MKCR9379

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Highly synchronized expression of lineage-specific genes during in vitro hepatic differentiation of human pluripotent stem cell lines
Ghosheh N, et al.
Stem Cells International, 2016 (2016)
Growth-suppressing and algicidal properties of an extract from Arundo donax, an invasive riparian plant, against Prymnesium parvum, an invasive harmful alga
Patino R, et al.
Harmful Algae, 71, 1-9 (2018)
Registration and Alignment Between in vivo Functional and Cytoarchitectonic Maps of Mouse Visual Cortex
Zhuang J, et al.
Bio-protocol, 8(4) (2018)
Chemical reaction monitoring via the light focusing in optofluidic waveguides.
Zhao HT, et al.
Sensors and Actuators B, Chemical, 280(4), 16-23 (2019)
Multi-layered, membrane-integrated microfluidics based on replica molding of a thiol-ene epoxy thermoset for organ-on-a-chip applications.
Sticker D, et al.
Lab on a chip, 15(24), 4542-4554 (2015)
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Articles

Acid and Base Chart — Table of Acids & Bases

Acid and base chart lists the strength of acids and bases (strongest to weakest) in order. Simple to use laboratory reference chart for scientists, researchers and lab technicians.

Acid and Base Chart — Table of Acids & Bases

Acid and base chart lists the strength of acids and bases (strongest to weakest) in order. Simple to use laboratory reference chart for scientists, researchers and lab technicians.

Acid and Base Chart — Table of Acids & Bases

Acid and base chart lists the strength of acids and bases (strongest to weakest) in order. Simple to use laboratory reference chart for scientists, researchers and lab technicians.

Acid and Base Chart — Table of Acids & Bases

Acid and base chart lists the strength of acids and bases (strongest to weakest) in order. Simple to use laboratory reference chart for scientists, researchers and lab technicians.

Protocols

Enzymatic Assay of Catalase (EC 1.11.1.6)

This procedure may be used for all Catalase products.

Enzymatic Assay of Ficin (EC 3.4.22.3)

This procedure may be used for all Ficin products.

Questions

1–7 of 7 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. How do I calculate the molarity of Product No. H1758, Hydrochloric acid?

    1 answer

    1. The molarity or molar concentration can be calculated using the following formula: [Density x 1000 x concentration (%)] / (molecular weight)

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  4. Is Product No. H1758, Hydrochloric acid, given a grade designation?

    1 answer

    1. This product is designated as Molecular Biology grade and is suitable for molecular biology applications.

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  5. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  6. How does the storage temperature relate to shipping conditions?

    1 answer

    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

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  7. What is the molarity or molar concentration of Product No. H1758, Hydrochloric acid?

    1 answer

    1. Based on an approximate density of 1.2 g/ml and a percentage range of 36.5 - 38.0%, concentrated HCl is in the range 11.6-12.0 M (which is also 11.6-12.0 Normal, for this monoprotic acid).

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