9-Anthroyl nitrile is a fluorescent reagent useful in the derivatization of glucocorticoids to aid their detection and separation using RP-HPLC with fluorescence detection. It forms fluorescent esters by reacting with primary the hydroxyl group at the position 21 of the carbon chain on the glucocorticoid .
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
For derivatization of hydroxyl compounds for HPLC with fluorescence detection[1].
Journal of chromatography. B, Biomedical sciences and applications, 718(2), 273-277 (1998-12-05)
Corticosteroids containing a C21 primary hydroxyl group were derivatised with 9-anthroyl cyanide. The reagent was prepared as a solution in acetonitrile, containing 0.1% triethylamine, at a concentration of 2 mg/ml. Approximately 1 microg of corticosteroid was reacted with 100 microl
The Journal of biological chemistry, 264(30), 18180-18187 (1989-10-25)
Hepatic parenchymal cells contribute to the clearance of circulating tissue-type plasminogen activator (t-PA) in vivo. The hepatocyte extracellular matrix is interposed between the endothelial-lined sinusoids and the parenchymal cell surface and thus may influence t-PA clearance. To test this hypothesis
A new ultrasensitive fluorescent derivatization procedure for chromatographic analysis of primary, secondary, and nonpolar tertiary alcohols is described. The procedure uses Bodipy FL in basic dichloromethane solution with Mukaiyama's reagent (2-chloro-1-methylpyridinium iodide) to form highly fluorescent ester derivatives that can
A nonradioisotopic method has been developed for the determination of all-trans-farnesyl pyrophosphate (FPP), the common intermediate at the branch point of the biosynthesis of cholesterol and nonsterol end products, in dog and human plasma. FPP was cleaved to the parent
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