Drug metabolism and pharmacokinetics, 26(5), 458-464 (2011-06-24)
The aim of this study was to determine whether administration of the prodrugs bisacodyl (Bisa) and sodium picosulfate (SPS) leads to excretion of their common active metabolite, bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), in breast milk. Two groups of 8 healthy lactating women who
Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 25(12), 657-662 (2011-12-17)
The ideal bowel cleansing regimen for colonoscopy has yet to be determined. To compare the cleansing efficacy, and patient tolerability and safety of four bowel preparation regimens. A total of 834 patients undergoing outpatient colonoscopy were randomly assigned to one
Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 25(12), 663-666 (2011-12-17)
Despite the wealth of research investigating bowel cleansing efficacy, there are very little data on the timing or frequency of bowel movements after each agent is ingested. To examine the effect of each component of a three-day combined sodium picosulphate⁄magnesium
Journal of pediatric gastroenterology and nutrition, 53(1), 71-74 (2011-06-23)
To assess the safety, efficacy, and acceptance of a 2-day bowel preparation with polyethylene glycol (PEG) 3350 without electrolytes and bisacodyl for colonoscopy in children. In a prospective study, 111 children of mean age 11.9 years were given 2 g/kg
Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk (2011)
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