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1.07144

Millipore

Papain

(from Carica papaya) water-soluble 30000 USP-U/mg for biochemistry EC 3.4.22.2

Synonym(s):

Papain Enzyme

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About This Item

UNSPSC Code:
12352204
NACRES:
NA.21
Pricing and availability is not currently available.

Quality Level

100

form

solid

pH

4-7 (25 °C, 1 g/L in H2O)

bulk density

800 kg/m3

storage temp.

2-30°C

Application


  • Novel biotechnological formulations of cysteine proteases, immobilized on chitosan. This study focuses on the development and characterization of innovative biotechnological formulations of cysteine proteases including papain, which are immobilized on chitosan to enhance their stability and activity. Such immobilization has significant implications for biopharmaceutical manufacturing processes, offering potential advancements in the stability and efficiency of biotechnological applications (Holyavka et al., 2021).

  • A novel aspartic protease from Rhizomucor miehei expressed in Pichia pastoris and its application on meat tenderization and preparation of turtle peptides. While primarily focusing on a novel aspartic protease, this research discusses comparative proteolytic activities including those of papain, highlighting its utility in improving the tenderness and quality of meat products, thus supporting its industrial application in food processing and life science manufacturing (Sun et al., 2018).

  • Comparison of the proteolytic activities of new commercially available bacterial and fungal proteases toward meat proteins. This comparative study assesses the efficacy of various proteases including papain in the breakdown of meat proteins. Papain′s effective proteolytic action is beneficial for its use in industrial and research settings, particularly in food science applications where efficient protein digestion is critical (Ha et al., 2013).


Analysis Note

Appearance (colour): yellowish-brown
Appearance (description): fine powder
Activity (Casein, pH 6.0, 40 °C): ≥ 30000 USP-U/mg
USP reference standard: calculated on USP reference standardJ0H138 (activity:6800 USP-U/mg)

Pictograms

Exclamation markHealth hazard
GHS07,GHS08

Signal Word

Danger

Hazard Statements

H315 - H319 - H334 - H335

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. I interest to your papain product. However, in the past we used papain in TU/mg unit. could you please inform me about how to convert TU/mg to USP unit. Thank you.

    1 answer

    1. 5047- USP U/mg = 90T U/mg, therefore 30000 USP-U/mg = 534.9790TU/mg.

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