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B84904

Sigma-Aldrich

2,3-Butanediol

98%

Synonym(s):

2,3-Butylene glycol

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About This Item

Linear Formula:
CH3CH(OH)CH(OH)CH3
CAS Number:
513-85-9
Molecular Weight:
90.12
Beilstein:
969165
EC Number:
208-173-6
MDL number:
MFCD00004523
UNSPSC Code:
12352100
PubChem Substance ID:
24892073
NACRES:
NA.22

Assay

98%

form

liquid

refractive index

n20/D 1.433 (lit.)

bp

183-184 °C (lit.)

mp

25 °C (lit.)

density

1.002 g/mL at 20 °C (lit.)

SMILES string

CC(O)C(C)O

InChI

1S/C4H10O2/c1-3(5)4(2)6/h3-6H,1-2H3

InChI key

OWBTYPJTUOEWEK-UHFFFAOYSA-N

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General description

2,3-Butanediol (2,3-BDO) is used as precursor in the synthesis of cyclic carbonates and methyl ethyl ketone.

Application

  • CRISPR/Cas9 in Pichia pastoris: 2,3-Butanediol (BDO) is used in the construction of P. pastoris cell factories as a representative example to demonstrate the procedures for integrating multiple heterologous genes using the CRISPR-based multiplex genome integration toolkit (Gao et al., 2024).
  • Antifungal activity in sorghum: 2,3-butanediol, a metabolite of A. oryzae YRA3, can induce the production of root exudates which modulate the growth of the rhizospheric fungi and bacteria (Rashad et al., 2023).

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

185.0 °F - closed cup

Flash Point(C)

85 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sustainable Synthesis of Non-Isocyanate Polyurethanes Based on Renewable 2, 3-Butanediol
A Kirchberg, et al.
Macromolecular Chemistry and Physics, 223, 2200010-2200010 (2022)
Natsuo Ueda et al.
Neuropharmacology, 48(8), 1079-1085 (2005-05-25)
It is widely accepted that fatty acid amide hydrolase (FAAH) plays a central role in the hydrolysis of anandamide. However, we found a second N-acylethanolamine hydrolase in animal tissues which hydrolyzed anandamide at acidic pH. This "acid amidase" was first
Patricia Hermand et al.
The Journal of biological chemistry, 278(7), 4892-4898 (2002-12-13)
ICAM-4 (LW blood group glycoprotein) is an erythroid-specific membrane component that belongs to the family of intercellular adhesion molecules and interacts in vitro with different members of the integrin family, suggesting a potential role in adhesion or cell interaction events
E Celińska et al.
Biotechnology advances, 27(6), 715-725 (2009-05-16)
Biotechnological production of 2,3-butanediol (hereafter referred to as 2,3-BD) from wastes and excessive biomass is a promising and attractive alternative for traditional chemical synthesis. In the face of scarcity of fossil fuel supplies the bio-based process is receiving a significant
Xiao-Jun Ji et al.
Biotechnology advances, 29(3), 351-364 (2011-01-29)
2,3-butanediol is a promising bulk chemical due to its extensive industry applications. The state-of-the-art nature of microbial 2,3-butanediol production is reviewed in this paper. Various strategies for efficient and economical microbial 2,3-butanediol production, including strain improvement, substrate alternation, and process
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