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A38401

Sigma-Aldrich

9-Aminoacridine hydrochloride monohydrate

98%

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About This Item

Empirical Formula (Hill Notation):
C13H10N2 · HCl · H2O
CAS Number:
52417-22-8
Molecular Weight:
248.71
Beilstein:
3707637
EC Number:
205-145-5
MDL number:
MFCD00150071
UNSPSC Code:
12352100
PubChem Substance ID:
24890818
NACRES:
NA.22

Quality Level

200

Assay

98%

form

powder

mp

300 °C (lit.)

λmax

400 nm
420 nm (2nd)

SMILES string

O.Cl.Nc1c2ccccc2nc3ccccc13

InChI

1S/C13H10N2.ClH.H2O/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13;;/h1-8H,(H2,14,15);1H;1H2

InChI key

OREJEGKBQBIJSJ-UHFFFAOYSA-N

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Application

Mutagen.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK6959
BCCG5883
BCCF5425
BCCD1970
BCCB8710

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Youn-Hwan Hwang et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 412736-412736 (2012-07-31)
Arisolochiae species plants containing aristolochic acids I and II (AA I and AA II) are well known to cause aristolochic acid nephropathy (AAN). Recently, there are various approaches to use AAs-containing herbs after the removal of their toxic factors. However
Nucleic acid-mutagen interactions: crystal structure of adenylyl-3',5'-uridine plus 9-aminoacridine.
N C Seeman et al.
Nature, 253(5490), 324-327 (1975-01-31)
Na Sun et al.
Hypertension (Dallas, Tex. : 1979), 75(3), 634-644 (2020-01-21)
Aldosterone-producing adenomas (APAs) are one of the main causes of primary aldosteronism and the most prevalent surgically correctable form of hypertension. Aldosterone-producing cell clusters (APCCs) comprise tight nests of zona glomerulosa cells, strongly positive for CYP11B2 (aldosterone synthase) in immunohistochemistry.
Masanori Murakami et al.
JCI insight, 4(17) (2019-09-06)
Recent genetic examinations and multisteroid profiles have provided the basis for subclassification of aldosterone-producing adenomas (APAs). The objective of the current study was to produce a comprehensive, high-resolution mass spectrometry imaging (MSI) map of APAs in relation to morphometry, immunohistochemical
Na Sun et al.
Endocrinology (2018-02-01)
In the adrenal gland, neuroendocrine cells that synthesize catecholamines and epithelial cells that produce steroid hormones are united beneath a common organ capsule to function as a single stress-responsive organ. The functional anatomy of the steroid hormone producing adrenal cortex
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