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Key Documents

564613

Sigma-Aldrich

5-Amino-2-nitrobenzoic acid

97%

Synonym(s):

2-Nitro-5-aminobenzoic acid, 3-Carboxy-4-nitroaniline, NSC 74455

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About This Item

Linear Formula:
H2NC6H3(NO2)CO2H
CAS Number:
Molecular Weight:
182.13
Beilstein:
2107512
EC Number:
MDL number:
UNSPSC Code:
12352106
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

236-238 °C (lit.)

application(s)

peptide synthesis

SMILES string

Nc1ccc(c(c1)C(O)=O)[N+]([O-])=O

InChI

1S/C7H6N2O4/c8-4-1-2-6(9(12)13)5(3-4)7(10)11/h1-3H,8H2,(H,10,11)

InChI key

KZZWQCKYLNIOBT-UHFFFAOYSA-N

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Application

Reactant for:
  • Two-component dendritic chain reactions
  • Enzymic activation of hydrophobic self-immolative dendrimers
  • Preparation of insulin receptor tyrosine kinase activator
  • Preparation of polymer-bound diazonium salts using Merrifield resin-bound piperazine

Pictograms

Flame over circle

Signal Word

Danger

Hazard Statements

Hazard Classifications

Ox. Sol. 2

Storage Class Code

5.1B - Oxidizing hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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A Balamurugan et al.
Biosensors & bioelectronics, 24(4), 982-986 (2008-09-09)
Herein, we reported for the first time one step procedure for the preparation of cytochrome c (cyt c)-poly (5-amino-2-napthalenesulfonic acid) (PANS) modified glassy carbon electrode by cyclic voltammetrically (CV). Hereafter, we called the above modified electrode as cyt c-PANS electrode.
Valeria Calcaterra et al.
Frontiers in pediatrics, 8, 591012-591012 (2020-12-18)
Background: Chronic low-grade inflammation and activation of the immune system are hallmark pathogenic mechanisms involved in metabolic dysfunction and are related to obesity. In particular, the involvement of regulatory and pro-inflammatory lymphocyte subpopulations has been reported in adults. We evaluated
5-amino-2-nitrobenzoic acid as a reference material for the determination of gamma-GT activity.
S Yamadate et al.
Clinica chimica acta; international journal of clinical chemistry, 160(1), 63-67 (1986-10-15)
F Schiele et al.
Clinical chemistry, 33(11), 1978-1982 (1987-11-01)
We describe the process of certification for a gamma-glutamyltransferase reference material (CRM no. 319). Fifteen laboratories participated to this interlaboratory evaluation. All steps of the measurements were controlled in an effort to locate potential sources of variations. In particular, the
Yu Jin Park et al.
Clinical biochemistry, 50(12), 719-725 (2017-03-05)
The use of iodinated contrast media has grown in popularity in the past two decades, but relatively little attention has been paid to the possible interferential effects of contrast media on laboratory test results. Herein, we investigate medical contrast media

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