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47639

Sigma-Aldrich

Fmoc-His(Trt)-OH

≥98.0% (sum of enantiomers, HPLC), for peptide synthesis

Synonym(s):

Nα-Fmoc-N(im)-trityl-L-histidine

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About This Item

Empirical Formula (Hill Notation):
C40H33N3O4
CAS Number:
109425-51-6
Molecular Weight:
619.71
Beilstein:
5204720
MDL number:
MFCD00043332
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
57651056
NACRES:
NA.26
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Product Name

Fmoc-His(Trt)-OH, ≥98.0% (sum of enantiomers, HPLC)

Assay

≥98.0% (sum of enantiomers, HPLC)

optical activity

[α]/D 87±5°, c = 1 in chloroform

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

OC(=O)[C@H](Cc1cn(cn1)C(c2ccccc2)(c3ccccc3)c4ccccc4)NC(=O)OCC5c6ccccc6-c7ccccc57

InChI

1S/C40H33N3O4/c44-38(45)37(42-39(46)47-26-36-34-22-12-10-20-32(34)33-21-11-13-23-35(33)36)24-31-25-43(27-41-31)40(28-14-4-1-5-15-28,29-16-6-2-7-17-29)30-18-8-3-9-19-30/h1-23,25,27,36-37H,24,26H2,(H,42,46)(H,44,45)/t37-/m0/s1

InChI key

XXMYDXUIZKNHDT-QNGWXLTQSA-N

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Application

Fmoc-His(Trt)-OH can be used as a building block in solid-phase peptide synthesis (SPPS).[1][2]

Analysis Note

may contain ~1 equivalent solvent

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM5598
BCCM5597
BCCH1027
BCCH0032
BCCJ0884

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Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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