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275573

Sigma-Aldrich

4-Hydroxybutyl acrylate

90%, contains 50 ppm monomethyl ether hydroquinone as inhibitor, 300 ppm hydroquinone as inhibitor

Synonym(s):

1,4-Butanediol acrylate, Tetramethylene glycol monoacrylate

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About This Item

Linear Formula:
H2C=CHCO2(CH2)4OH
CAS Number:
Molecular Weight:
144.17
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

Assay

90%

contains

300 ppm hydroquinone as inhibitor
50 ppm monomethyl ether hydroquinone as inhibitor

refractive index

n20/D 1.452 (lit.)

bp

95 °C/0.1 mmHg (lit.)

density

1.041 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

OCCCCOC(=O)C=C

InChI

1S/C7H12O3/c1-2-7(9)10-6-4-3-5-8/h2,8H,1,3-6H2

InChI key

NDWUBGAGUCISDV-UHFFFAOYSA-N

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General description

4-Hydroxybutyl acrylate (HBA) can be synthesized by the esterification of acrylic acid with 1, 4 butanediol over a catalyst such as Amberlyst 15. 4-Hydroxybutyl acrylate (HBA) exhibits properties such as luster, chemical and scratch resistance. HBA monomers may be used as one of the constituents for the fabrication of a membrane system for controlled release of transdermal drug delivery system.

Application

Hydroxybutyl acrylate was one of the monomers utilized in the preparation of poly(2-hydroxy-3-phenoxypropylacrylate, 4-hydroxybutyl acrylate, dibutyl maleate) membranes.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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A new poly(2-hydroxy-3-phenoxypropylacrylate, 4-hydroxybutyl acrylate, diethyl maleate) membrane controlled clonidine linear release in the transdermal drug delivery system.
Zhan X< et al.
European Polymer Journal, 43(4), 83-91 (2007)
Agnieszka Kowalczyk et al.
Polymers, 11(12) (2019-12-15)
New organic-inorganic hybrid copolymers (EA-POSSs) based on butyl acrylate, glycidyl methacylate, hydroxybutyl acrylate, acryloiloxybenzophenone and acryloxypropyl-heptaisobutyl-POSS (A-POSS) were prepared via free-radical solution polymerization (FRP) and applied as a component of thermally curable structural self-adhesive tapes (SATs). The EA-POSS with 0.25
A new poly(2-hydroxy-3-phenoxypropylacrylate, 4-hydroxybutyl acrylate, diethyl maleate) membrane controlled clonidine linear release in the transdermal drug delivery system.
Zhan X, et al.
European Polymer Journal, 43(4), 1588-1594 (2007)
Qian Zhao et al.
Journal of materials chemistry. B, 8(40), 9362-9373 (2020-10-01)
A series of novel nanofibrillated cellulose (NFC) reinforced gradient intelligent hydrogels with high response rate, multiple response patterns and diversified self-driven functions were successfully prepared. Based on the effect of the hydroxide radical of NFC on the addition reaction, and
Xiaoping Zhan et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 66(3), 429-434 (2007-01-02)
Poly(2-hydroxy-3-phenoxypropylacrylate, 4-hydroxybutyl acrylate, dibutyl maleate) membrane was synthesized by UV curing method in our laboratory for the first time. When above-mentioned monomers were in the weight ratio of 4:4:2, the membrane not only had perfect permeation property but also had

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