Skip to Content
Merck
All Photos(3)

Documents

224936

Sigma-Aldrich

4-(Trifluoromethyl)aniline

99%

Synonym(s):

α,α,α-Trifluoro-p-toluidine, 4-Aminobenzotrifluoride

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Linear Formula:
CF3C6H4NH2
CAS Number:
455-14-1
Molecular Weight:
161.12
Beilstein:
1564853
EC Number:
207-236-5
MDL number:
MFCD00064396
UNSPSC Code:
12352100
PubChem Substance ID:
24853465
NACRES:
NA.22

Assay

99%

form

liquid

refractive index

n20/D 1.483 (lit.)

bp

83 °C/12 mmHg (lit.)

density

1.283 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

Nc1ccc(cc1)C(F)(F)F

InChI

1S/C7H6F3N/c8-7(9,10)5-1-3-6(11)4-2-5/h1-4H,11H2

InChI key

ODGIMMLDVSWADK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

4-(Trifluoromethyl)aniline was used in the synthesis of 4-(trialkylmethyl)anilines. It was also used as a synthetic building block.

Signal Word

Danger

Hazard Statements

H301,H318,H410

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A Facile Synthesis of 4-(Trialkylmethyl) anilines by the Reaction of 4-(Trifluoromethyl) aniline with Grignard Reagents.
Synthetic Communications, 27(11), 1975-1980 (1997)
L M Angerer et al.
Developmental biology, 149(1), 27-40 (1992-01-01)
We have identified an mRNA that encodes a protein, SpS24, of the small ribosomal subunit in the sea urchin, Strongylocentrotus purpuratus. RNA blot and in situ hybridization analyses show that the SpS24 gene is active during early oogenesis, downregulated in
T Koivula et al.
Gene, 119(1), 145-146 (1992-09-21)
A cloned fragment from Lactococcus lactis chromosome encoding the L33 ribosomal protein was sequenced. Two incomplete open reading frames (ORFs) were also found: the upstream ORF shows similarity to the tetracycline-resistance protein (Tet) of Bacillus stearothermophilus, and the downstream ORF
Tetrahedron Letters, 48, 4749-4749 (2007)
Meritxell Guinó et al.
The Journal of organic chemistry, 72(16), 6290-6293 (2007-07-13)
Optically active torcetrapib was synthesized in seven steps from achiral precursors without the need for protecting groups, utilizing an enantioselective aza-Michael reaction to achieve asymmetry.
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service