196479
2-Phenyl-4-quinolinecarboxylic acid
99%
Synonym(s):
2-Phenylcinchoninic acid, Cinchophen
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About This Item
Empirical Formula (Hill Notation):
C16H11NO2
CAS Number:
Molecular Weight:
249.26
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
99%
form
powder
mp
214-215 °C (lit.)
solubility
alcohol: soluble 1g in 120ml(lit.)
chloroform: soluble 1g in 400ml(lit.)
diethyl ether: soluble 1g in 100ml(lit.)
water: insoluble(lit.)
SMILES string
OC(=O)c1cc(nc2ccccc12)-c3ccccc3
InChI
1S/C16H11NO2/c18-16(19)13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H,(H,18,19)
InChI key
YTRMTPPVNRALON-UHFFFAOYSA-N
Related Categories
General description
2-Phenyl-4-quinolinecarboxylic acid on reaction with 5-aryl-2,3-dihydro-2,3-furandiones yields β-aroylpyruvoyl hydrazide of 2-phenyl-4-quinolinecarboxylic acid.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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[Gout].
Y OSHIMA
Naika. Internal medicine, 10, 1101-1102 (1962-12-01)
[DISTRIBUTION AND CONTENT OF RIBONUCLEOPROTEINS IN THE SMALL INTESTINE MUCOUS MEMBRANE IN CHRONIC EXPERIMENTAL STOMACH ULCER IN DOGS].
S A DALIMOV et al.
Meditsinskii zhurnal Uzbekistana, 39, 50-53 (1963-08-01)
Carrageenin and cinchophen ulcer.
R B FIGUEROA et al.
Current therapeutic research, clinical and experimental, 5, 70-74 (1963-02-01)
H Jingu et al.
Neuroreport, 7(15-17), 2649-2653 (1996-11-04)
This study aimed at obtaining evidence that cinchophen, an ulcerogenic drug, stimulates the corticotropin-releasing hormone (CRH)-secreting cells in the paraventricular nucleus of the hypothalamus (PVH) to induce c-Fos expression. Without colchicine pretreatment, cinchophen was injected i.p. 60 min before the
S G Krylova et al.
Eksperimental'naia i klinicheskaia farmakologiia, 63(2), 44-47 (2000-06-02)
Dry aspen bark extract exhibits pronounced antiulcerogenic activity as demonstrated by the results of experiments using the models of histamine and atophan induced ulcers and the ulceration model according to H. Shay. The gastroprotector activity is manifested by decreasing number
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