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1012553

USP

Albendazole

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Methyl 5-(propylthio)-2-benzimidazolecarbamate

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About This Item

Empirical Formula (Hill Notation):
C12H15N3O2S
CAS Number:
54965-21-8
Molecular Weight:
265.33
MDL number:
MFCD00083232
UNSPSC Code:
41116107
PubChem Substance ID:
329748945
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

albendazole

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChI key

HXHWSAZORRCQMX-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Albendazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Albendazole Oral Suspension
  • Albendazole Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Pictograms

Health hazardEnvironment
GHS08,GHS09

Signal Word

Warning

Hazard Statements

H361d,H373,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral

Target Organs

Adrenal gland,Blood,male reproductive organs,spleen

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Julia Critchley et al.
Tropical medicine & international health : TM & IH, 10(9), 818-825 (2005-09-02)
The Global Programme to Eliminate Lymphatic Filariasis recommends albendazole in combination with other antifilarial drugs. This systematic review examines albendazole in treatment and control of lymphatic filariasis. DATASOURCES: The Cochrane Controlled Trials Register, MEDLINE and EMBASE to April 2005; contacting
Matthew E Falagas et al.
The American journal of the medical sciences, 334(3), 171-179 (2007-09-18)
Albendazole has been used in various ways in the treatment of cystic echinococcosis (CE). We reviewed the available evidence regarding the role of albendazole for the treatment of patients with CE. The available comparative clinical trials (randomized or not) that
M E Oxberry et al.
Journal of veterinary pharmacology and therapeutics, 23(3), 113-120 (2000-12-08)
Trophozoites of the protozoan parasite Giardia duodenalis were exposed to various albendazole concentrations for 4 h, washed, fixed and incubated with antibodies raised against albendazole and its two major metabolites albendazole sulphoxide and albendazole sulphone. Tubulin antibodies were also used.
J Horton
Annals of tropical medicine and parasitology, 103 Suppl 1, S33-S40 (2009-11-11)
The history of the development of ivermectin and diethylcarbamazine for the treatment of human filarial infections is relatively well known and documented. The story of how albendazole became involved in the global elimination programmes is, however, less well known. This
John Horton
Current opinion in infectious diseases, 15(6), 599-608 (2003-06-25)
It is over 25 years ago since the original animal research was conducted into albendazole. This review highlights some important steps in fundamental research and the management of helminth disease that have occurred in the past year, appearing in the
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