S0802
Stearoyl coenzyme A lithium salt
≥90%
Synonym(s):
n-Octadecanoyl Coenzyme A
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About This Item
Recommended Products
Assay
≥90%
storage temp.
−20°C
Application
Coenzyme A functions as an acyl group carrier, acetyl-CoA. Stearoyl CoA is a saturated fatty acid metabolite involved in polyunsaturated fatty acid synthesis and the PPAR signaling pathway. Stearoyl CoA is used to study the specificity and kinetics of stearoyl-CoA desaturase(s) which lead to the formation of monounsaturated fatty acids.
Stearoyl coenzyme A lithium salt may be used as a substrate in the stearoyl-CoA desaturase assay in microsomes.
Biochem/physiol Actions
Stearoyl CoA is a saturated fatty acid metabolite involved in polyunsaturated fatty acid synthesis and the PPAR signaling pathway. Stearoyl CoA is a substrate for the enzyme stearoyl-CoA desaturase. Stearoyl CoA desaturation is the crucial step in unsaturated fatty acid biosynthesis. Stearoyl CoA is converted to oleoyl-CoA by stearoyl-CoA desaturase.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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The Journal of Biological Chemistry, 275(39), 30132-30138 (2000)
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity
Proceedings of the National Academy of Sciences of the USA, 99(17), 11482-11486 (2002)
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