PLA0057

Rabbit anti-Mre11 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(s): AT-like disease, ATLD, DNA recombination and repair protein, HNGS1, MRE11, MRE11 double strand break repair nuclease A, MRE11 homolog, MRE11 homolog 1, MRE11 homolog A, MRE11 meiotic recombination 11 homolog A, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), MRE11 meiotic recombination 11-like protein A, MRE11B, double strand break repair nuclease A, endo/exonuclease Mre11, meiotic recombination (S. cerevisiae) 11 homolog A, meiotic recombination 11 homolog 1, meiotic recombination 11 homolog A
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• grade: Powered by Bethyl Laboratories, Inc.
• species reactivity: human
• technique(s): immunohistochemistry: 1:1,000-1:5,000; western blot: 1:1,000- 1:5,000
• accession no.: NP_005582.1
• UniProt accession no.: P49959
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: rabbit ... Mre11(4361)

Description

Immunogen

The epitope recognized by PLA0057 maps to a region between residues 1 and 50 of human Meiotic Recombination 11 homolog A using the numbering given in entry NP_005582.1 (GeneID 4361).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Other Notes

Mre11 is a component of the MRN complex and plays a role in telomere maintenance and double-strand break (DSB) repair. Mre11 associates with rad50 in the MRN complex. Mre11 possesses 3′– 5′ exonuclease activity that is involved in creating DNA termini in DSB suitable for priming DNA synthesis and ligation.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable