O5507
Linoleic acid, conjugated
Synonym(s):
CLA, Octadecadienoic acid, conjugated
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About This Item
UNSPSC Code:
12352211
NACRES:
NA.77
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General description
A mixture of cis- and trans-9,11- and -10,12-octadecadienoic acids. Isomer ratio may vary from lot to lot.
Application
- A targeted nanomodulator capable of manipulating tumor microenvironment against metastasis.: The paper discusses the development of a targeted nanomodulator, including conjugated linoleic acid, to manipulate the tumor microenvironment and inhibit metastasis. The findings suggest significant potential for improved cancer treatments (Tian et al., 2022).
- Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.: The research focuses on hyaluronic acid-modified nanoparticles using linoleic acid-conjugated chitosan for the codelivery of miR34a and doxorubicin. This approach aims to overcome drug resistance in breast cancer treatments (Yang et al., 2022).
Biochem/physiol Actions
Potent inhibitor of breast, skin, and colon carcinogenesis and tumor cell proliferation; inhibits bFGF-induced endothelial cell proliferation; potent antioxidant.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Rui Guo et al.
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Dietary fat composition is closely associated with the pathological development of alcoholic liver disease (ALD). Fat enriched with saturated fatty acids protects whereas with polyunsaturated fatty acids aggravates alcohol-induced liver injury. However, limited study has addressed how monounsaturated fatty acids
Christina Donnelly et al.
Nutrition and cancer, 61(1), 114-122 (2009-01-01)
Spot 14 (THRSP, S14) is a nuclear protein involved in the regulation of genes required for fatty acid synthesis in normal and malignant mammary epithelial and adipose cells. Harvatine and Bauman (1) reported that conjugated linoleic acid (CLA) inhibits S14
Daeun Lee et al.
Archives of pharmacal research, 43(4), 449-461 (2020-04-03)
Schizophyllan (SPG), produced by Schizophyllum commune, is an exopolysaccharide with multiple academic and commercial uses, including in the food industry and for various medical functions. We previously demonstrated that SPG conjugated with c-Src peptide exerted a significant therapeutic effect on
Swati Shivani et al.
Journal of the science of food and agriculture, 96(5), 1716-1722 (2015-05-29)
Conjugated linoleic acid (CLA) isomers have high health amelioration potential and hence it is of great interest to increase the CLA content in dairy products. The present study was conducted to investigate the effect of administration of high CLA producing
M S Vela Gurovic et al.
Food & function, 6(11), 3437-3443 (2015-08-25)
Chitooligosaccharides (COSs) have been clinically evaluated for their immunostimulating effects after oral intake. Similar to dietary supplements, prebiotics and biopreservatives, these water-soluble bioactives are easily incorporated into dairy products and beverages. Notwithstanding, the use of COS in fermented foods would
Articles
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
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