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Key Documents

T1950000

Triamcinolone hexacetonide

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(11β,16α)-21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione

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About This Item

Empirical Formula (Hill Notation):
C30H41FO7
CAS Number:
5611-51-8
Molecular Weight:
532.64
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

triamcinolone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C30H41FO7/c1-25(2,3)15-24(35)36-16-22(34)30-23(37-26(4,5)38-30)13-20-19-9-8-17-12-18(32)10-11-27(17,6)29(19,31)21(33)14-28(20,30)7/h10-12,19-21,23,33H,8-9,13-16H2,1-7H3/t19-,20-,21-,23+,27-,28-,29-,30+/m0/s1

InChI key

TZIZWYVVGLXXFV-FLRHRWPCSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Triamcinolone hexacetonide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

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Dimitrios Makrygiannakis et al.
Arthritis research & therapy, 14(1), R20-R20 (2012-01-31)
Protein citrullination is present in the rheumatoid synovium, presumably contributing to the perpetuation of chronic inflammation, in the presence of specific autoimmunity. As a result, the present study examined the possibility that effective antirheumatic treatment will decrease the level of
Marla Francisca Dos Santos et al.
Clinical rheumatology, 30(1), 77-85 (2010-12-02)
The aim of the present study was to investigate the long-term effectiveness of and tolerance to Yttrium-90 and Samarium-153-particulate hydroxyapatite radiation synovectomy in patients with rheumatoid arthritis (RA) and chronic knee synovitis. Eight-four patients (90 knees) with chronic knee synovitis
Subcutaneous calcification following injection of triamcinolone hexacetonide for plantar fasciitis.
R R Raghavendran et al.
Rheumatology (Oxford, England), 47(12), 1838-1838 (2008-10-03)
Emmanuelle Dernis et al.
Joint, bone, spine : revue du rhumatisme, 77(5), 451-457 (2010-05-18)
To develop recommendations about the use of glucocorticoids in patients with established rheumatoid arthritis (RA) managed in everyday practice, using the evidence-based approach and expert opinion. A three-step procedure was used: a scientific committee used a Delphi procedure to select
Zalima N Jahangier et al.
Clinical rheumatology, 30(6), 749-755 (2010-11-17)
To investigate whether ultrasonographic joint assessment can predict the clinical response to intra-articular injection therapy of the knee. Patients with persistent gonarthritis intra-articularly received in a randomized double-blinded crossover fashion radiation synovectomy or a glucocorticoid injection, both followed by clinical
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