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SMB01380

Sigma-Aldrich

4-Methoxyestrone

≥95% (HPLC), from synthetic, solid

Synonym(s):

3-Hydroxy-4-methoxyestra-1,3,5(10)-trien-17-one

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About This Item

Empirical Formula (Hill Notation):
C19H24O3
CAS Number:
58562-33-7
Molecular Weight:
300.39
MDL number:
MFCD00199041
UNSPSC Code:
51111800
NACRES:
NA.25

biological source

synthetic

Quality Level

200

Assay

≥95% (HPLC)

form

solid

storage condition

(Heat sensitive)

storage temp.

2-8°C

SMILES string

C[C@@]12[C@](CCC2=O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O)C(OC)=C4CC3

General description

4-Methoxyestrone is an endogenous, naturally occurring methoxylated catechol estrogen and an estrone metabolite formed by catechol O-methyltransferase via the intermediate 4-hydroxyestrone. It has estrogenic activity similarly to estrone and 4-hydroxyestrone.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H351,H360FD,H362

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000238156
0000238157
0000226524
0000226523
0000221875

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Reproducibility of fifteen urinary estrogens and estrogen metabolites over a 2- to 3-year period in premenopausal women
Heather A, et al.
Cancer Epidemiology, Biomarkers & Prevention, 18, 2860-2868 (2009)
Urinary estrogen metabolites and gastric cancer risk among postmenopausal women
Constanza M, et al.
Cancer reports (Hoboken, N.J.), 5, e1574-e1574 (2021)
Individual and cyclic estrogenic profile in women: Structure and variability of the data
Bozzolino Cristina, et al.
Steroids, 150, 108432-108432 (2019)

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