07579
Synperonic® F 108
surfactant, non-ionic
Synonym(s):
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), Poly(propylene glycol)-block-poly(ethylene glycol)-block-poly(propylene glycol)
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About This Item
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Quality Level
impurities
≤0.5% water
mp
56-61 °C
hydroxyl value
6‑9 mg KOH/g
application(s)
detection
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChI key
RVGRUAULSDPKGF-UHFFFAOYSA-N
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General description
Synperonic F-108 is a polyoxyethylene-polyoxypropylene block copolymer. It has two hydrophilic groups that are attached to a central hydrophobic group that self-assembles in an aqueous solution into clusters known as micelles. This water-soluble surfactant is used as effective emulsification and solubilizing agent in a wide range of applications.
Application
Synperonic® F 108 may be used as an adjuvant for lentiviral (LV) transduction. It possesses higher (LV) transduction efficiency than polybrene.
Legal Information
Synperonic is a registered trademark of Croda International PLC
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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In this study, curcumin (Cur) loaded mixed micelles (Cur-PF), composed of Pluronic P123 (P123) and Pluronic F68 (F68), was prepared using the thin-film hydration method and evaluated in vitro. The preparation process was optimized with a central composite design (CCD).
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