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475818

Sigma-Aldrich

Microcystin-LW, Microcystis aeruginosa

Analog of Microcystin-LR with Trp substituted in place of Arg. Believed to be more cell-permeable than other microcystins making it useful for biochemical studies in intact cells.

Synonym(s):

Microcystin-LW, Microcystis aeruginosa, MCYST-LW

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About This Item

Empirical Formula (Hill Notation):
C54H72N8O12
Molecular Weight:
1025.20
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥95% (HPLC)

form

film

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

colorless

solubility

methanol: 2 mg/mL
DMSO: 2.5 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

Analog of Microcystin-LR (Cat. No 475815) with Trp group substituted in place of Arg. Believed to be more cell-permeable than other microcystins, making it useful for biochemical studies in intact cells.
Analog of Microcystin-LR (Cat. No. 475815) with Trp substituted in place of Arg. Believed to be more cell-permeable than other microcystins making it useful for biochemical studies in intact cells.

Biochem/physiol Actions

Cell permeable: yes
Product does not compete with ATP.
Reversible: no

Packaging

yes

Warning

Toxicity: Highly Toxic (H)

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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L A Lawton et al.
The Analyst, 119(7), 1525-1530 (1994-07-01)
Increasing concern over the presence of microcystins (cyanobacterial/blue-green algal hepatotoxins) in water supplies has emphasized the need for a suitable analytical method. As many microcystins are known to exist, a method was developed that permits the determination of numerous variants
L A Lawton et al.
Natural toxins, 3(1), 50-57 (1995-01-01)
Six microcystins were identified in a laboratory culture of the cyanobacterium (blue-green alga) Microcystis aeruginosa PCC 7813 using high-performance liquid chromatography coupled with diode array detection (HPLC-DAD) and mass spectrometry (LC-MS). The toxins were purified and further characterized by amino

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