247162

Ethyl propionylacetate

97%

• Synonym(s): Ethyl 3-oxovalerate
• Linear Formula: CH₃CH₂COCH₂COOC₂H₅
• CAS Number: 4949-44-4
• Molecular Weight: 144.17
• Beilstein: 970270
• EC Number: 225-593-5
• MDL number: MFCD00009317
• UNSPSC Code: 12352100
• PubChem Substance ID: 24854855
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• form: liquid
• refractive index: n20/D 1.422 (lit.)
• bp: 83-84 °C/12 mmHg (lit.)
• density: 1.012 g/mL at 25 °C (lit.)
• SMILES string: CCOC(=O)CC(=O)CC
• InChI: 1S/C7H12O3/c1-3-6(8)5-7(9)10-4-2/h3-5H2,1-2H3
• InChI key: UDRCONFHWYGWFI-UHFFFAOYSA-N

Description

General description

Ethyl propionylacetate reacts with tropolone p-toluenesulfonate in the presence of sodium ethoxide to give 3-propionyl-2H-cyclohepta[b]furan-2-one.

Application

Ethyl propionylacetate has been used in the synthesis of 1-ethyl- and 1-n-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid bearing one or two substituents on the benzene ring.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 172.4 °F - closed cup
• Flash Point(C): 78 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves