149225
Dipropyl disulfide
98%
Synonym(s):
Propyl disulfide
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About This Item
Linear Formula:
CH3CH2CH2SSCH2CH2CH3
CAS Number:
Molecular Weight:
150.31
Beilstein:
969200
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Assay
98%
form
liquid
refractive index
n20/D 1.497 (lit.)
bp
195-196 °C (lit.)
mp
−86 °C (lit.)
density
0.96 g/mL at 25 °C (lit.)
functional group
disulfide
SMILES string
CCCSSCCC
InChI
1S/C6H14S2/c1-3-5-7-8-6-4-2/h3-6H2,1-2H3
InChI key
ALVPFGSHPUPROW-UHFFFAOYSA-N
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General description
Dipropyl disulfide (DPDS) was an efficient scavenger of reactive oxygen species (ROS) at a lower concentration in both HL-60 and HepG2 cells. It prevents the oxidative DNA damage caused by N-nitrosopiperidine (NPIP) and N-nitrosodibutylamine (NDBA).
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
147.2 °F - closed cup
Flash Point(C)
64 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Opender Koul
Journal of economic entomology, 97(3), 1142-1147 (2004-07-29)
Head space volatiles, including 73% di-n-propyl disulfide, were collected from freshly crushed neem seeds. This compound along with previously reported diallyl disulfide (di-2-propenyl disulfide) were toxic when applied topically or as a fumigant to Tribolium castaneum adults and 8-, 12-
Effects of oil-soluble organosulfur compounds from garlic on doxorubicin-induced lipid peroxidation.
C Dwivedi et al.
Anti-cancer drugs, 9(3), 291-294 (1998-06-13)
Clinical efficacy of doxorubicin is compromised due to free radical generation leading to cardiac toxicity. Oil-soluble organosulfur compounds, diallyl sulfide (DAS), diallyl disulfide (DADS), dipropyl sulfide (DPS) and dipropyl disulfide (DPDS), present in garlic were examined for their antiperoxidant effects.
M H Siess et al.
Cancer letters, 120(2), 195-201 (1998-02-14)
Natural compounds which elevate detoxification enzymes and/or reduce activating enzymes could be considered as good candidates to protect against cancer. In this work, we studied the modulation of hepatic drug-metabolizing enzymes in rats treated with dimethyl sulfide (DMS), dimethyl disulfide
S V Singh et al.
Biochemical and biophysical research communications, 244(3), 917-920 (1998-04-16)
This study was undertaken to elucidate the mechanism of organ specificity and differential efficacy of garlic organosulfides (OSCs) [diallyl sulfide (DAS), diallyl disulfide (DADS), diallyl trisulfide (DATS), dipropyl sulfide (DPS) and dipropyl disulfide (DPDS)] in preventing benzo(a)pyrene (BP)-induced tumorigenesis in
X Hu et al.
International journal of cancer, 73(6), 897-902 (1997-12-17)
There is a growing need for short-term and cost-effective bioassay to assess the efficacy of potential chemo-preventive agents. We report that the induction of glutathione (GSH) S-transferase pi (mGSTP1-1) by a chemo-preventive agent can be used as a reliable marker
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