Skip to Content
Merck
All Photos(1)

Documents

P2918

Sigma-Aldrich

Human Serum

from platelet poor human plasma, sterile-filtered, (mycoplasma tested, virus tested)

Synonym(s):

human plasma, human sera, human serum

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

MDL number:
MFCD00165829
UNSPSC Code:
12352207
NACRES:
NA.71

biological source

human

sterility

sterile-filtered

origin

USA origin

technique(s)

cell culture | mammalian: suitable

impurities

(mycoplasma tested, virus tested)
≤10 EU/mL endotoxin

shipped in

dry ice

storage temp.

−20°C

Looking for similar products? Visit Product Comparison Guide

General description

The serum is the fluid part of the blood containing plasma without fibrinogen.

Application

Human Serum has been used:
  • in the preparation of human serum samples that mimic the COVID-19 patient samples for serological antibody testing
  • as a media supplement to differentiate human induced pluripotent stem cells (hiPS) to hiPS- brain microvascular endothelial cells (BMEC)
  • for culturing transgenic Plasmodium falciparum clone
  • for assessing the electrochemical response of recombinant P. falciparum parasite L-lactate dehydrogenase (LDH) in serum samples
  • in platelet-derived growth factor (PDGF) purification assays

Human serum from platelet poor plasma (PPP) is useful for studies of the effects of platelet lysates on the growth of cells such as articular chondrocytes and human skin fibroblasts. It has also been used in platelet derived growth factor (PDGF) purification assays.

Biochem/physiol Actions

Serum serves as a supplement to basal media formulations and conventional biomedical cell culture media. It acts as a source of trace nutrients, signaling molecules, growth factors, and hormones that induce proper cell growth in vitro. Human serum from platelet-poor plasma (PPP) is useful in the studies of the effects of platelet lysates on the growth of cells such as articular chondrocytes and human skin fibroblasts.

Analysis Note

Endotoxin tested

Other Notes

It is not unusual for a white precipitate to form following a freeze-thaw cycle for this human serum product.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Physiology, Blood Plasma null
Edward N O'Neill et al.
Comprehensive reviews in food science and food safety, 20(1), 686-709 (2020-12-17)
Innovation in cultivated meat development has been rapidly accelerating in recent years because it holds the potential to help attenuate issues facing production of dietary protein for a growing world population. There are technical obstacles still hindering large-scale commercialization of
Y Umeno et al.
Journal of cell science, 94 ( Pt 3), 567-575 (1989-11-01)
We examined the proliferative behaviour in tertiary culture cells of human skin fibroblasts (HSF) as well as cells of the rat 3Y1 diploid fibroblast line placed on a plastic substratum in a nutrient-rich medium containing high concentrations of platelet-poor plasma
Aver Hemben et al.
Talanta, 187, 321-329 (2018-06-02)
This paper describes the development of an affinity sensor for the detection of Plasmodium falciparum parasite lactate dehydrogenase (pLDH) as one of the biomarkers used for malaria detection. The gold sensor was functionalised with anti-pLDH after cleaning the electrode surface
Y C Choi et al.
Arthritis and rheumatism, 23(2), 220-224 (1980-02-01)
Human platelet lysate (PL) has a strong growth promoting action on rabbit articular chondrocytes in monolayer culture. The responsible factor is heat stable (56 degrees C, 30 minutes) and above 10,000 MW. PL (80 microgram protein/ml) reduces cell protein content
View All Related Papers

Articles

Serum for Cell and Tissue Culture FAQs

Find answers to frequently asked questions (FAQs) about FBS and other serum products, and links to related products.

Serum for Cell and Tissue Culture FAQs

Find answers to frequently asked questions (FAQs) about FBS and other serum products, and links to related products.

Serum for Cell and Tissue Culture FAQs

Find answers to frequently asked questions (FAQs) about FBS and other serum products, and links to related products.

Serum for Cell and Tissue Culture FAQs

Find answers to frequently asked questions (FAQs) about FBS and other serum products, and links to related products.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service