C4418
L-Cysteinesulfinic acid monohydrate
Synonym(s):
3-Sulfinoalanine
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About This Item
Empirical Formula (Hill Notation):
C3H7NO4S · H2O
CAS Number:
Molecular Weight:
171.17
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.32
Recommended Products
form
powder
storage temp.
−20°C
SMILES string
NC(CS(O)=O)C(O)=O
InChI
1S/C3H7NO4S/c4-2(3(5)6)1-9(7)8/h2H,1,4H2,(H,5,6)(H,7,8)
InChI key
ADVPTQAUNPRNPO-UHFFFAOYSA-N
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Application
L-Cysteinesulfinic acid monohydrate has been used in the fluorescence measurement of cysteine oxidation.
Biochem/physiol Actions
Cysteinesulfinic acid (CSA), also called 3-sulfinoalanine is synthesized by the conversion of sulfur to sulfinic acid in cysteine by the enzyme cysteine dioxygenase (CDO). CSA is a putative excitatory amino acid (EAA) with neurotransmitter functionality. It also regulates cardiovascular functions.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Oxidation of hypotaurine and cysteine sulphinic acid by peroxynitrite
Fontana M, et al.
The Biochemical Journal, 389(1), 233-240 (2005)
Cysteine sulphinate (CSA) as an excitatory amino acid transmitter candidate in the mammalian central nervous system.
R Griffiths
Progress in neurobiology, 35(4), 313-323 (1990-01-01)
Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels
Stipanuk MH, et al.
Amino Acids, 37(1), 55-55 (2009)
Cardiovascular actions of L-cysteine and L-cysteine sulfinic acid in the nucleus tractus solitarius of the rat
Takemoto Y
Amino Acids, 46(7), 1707-1713 (2014)
N-acetyl cysteine functions as a fast-acting antioxidant by triggering intracellular H2S and sulfane sulfur production
Ezericna D, et al.
Cell Chemical Biology, 25(4), 447-459 (2018)
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