P-122

Prednisone solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₂₁H₂₆O₅
• CAS Number: 53-03-2
• Molecular Weight: 358.43
• MDL number: MFCD00003608
• UNSPSC Code: 41116107
• PubChem Substance ID: 329820080
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in acetonitrile
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• mp: -48 °C
• density: 0.78 g/cm³ at 20 °C
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• InChI: 1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
• InChI key: XOFYZVNMUHMLCC-ZPOLXVRWSA-N
• Gene Information: human ... NR3C1(2908)

Description

General description

Calibration standard and quality control for calibration or identification of prednisone in biological samples for mass spectrometry-based clinical testing applications including therapeutic drug monitoring, endocrinology, cancer treatment, and confirming the cause of secondary adrenal insufficiency. Prednisone is a synthetic corticosteroid drug used to treat a variety of inflammatory diseases and conditions.

Application

• A Breath of Relief: Oxymetazoline and Flunisolide Nasal Spray in the Management of Myasthenia Gravis Ptosis.: This study explores the use of corticosteroid solutions, like Prednisone, in managing inflammatory conditions. Prednisone solution is essential for understanding its anti-inflammatory effects in clinical settings and can be applied in biochemistry and cell signaling studies (Aloyan et al., 2024).


• Remission and low disease activity are associated with lower healthcare costs: results from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort.: Prednisone solution is highlighted for its role in achieving remission and low disease activity in autoimmune diseases like lupus, emphasizing its importance in laboratory and clinical research for autoimmune and inflammatory conditions (Barber et al., 2024).


• Freeze-dried amniotic membrane graft with a spongy layer in bilateral peripheral ulcerative keratitis: a case report.: This case report discusses the application of Prednisone solution in treating severe inflammatory eye conditions, demonstrating its use in autoimmune disease and inflammatory response research (Bertret et al., 2023).


• 2023 Canadian Thoracic Society Guideline on Pharmacotherapy in Patients With Stable COPD.: Prednisone solution is part of the pharmacotherapy guidelines for managing chronic inflammatory respiratory conditions like COPD, showcasing its relevance in asthma treatment and biochemistry studies focused on respiratory inflammation (Bourbeau et al., 2023).


• Retrospective Analysis With Propensity Score Matching of Peripheral T-Cell Lymphoma Treated Frontline With Brentuximab Vedotin and Chemotherapy.: This research highlights the role of Prednisone solution in oncology, specifically in managing inflammatory responses during cancer treatment, making it crucial for pharmacological experimentation in cancer and inflammation research (Burke et al., 2023).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302 + H312 + H332,H319
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 35.6 °F - closed cup
• Flash Point(C): 2.0 °C - closed cup