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880200P

Avanti

16:0 PEG5000 PE

Avanti Research™ - A Croda Brand 880200P, powder

Synonym(s):

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] (ammonium salt)

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About This Item

CAS Number:
474922-84-4
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 g (880200P-1g)
pkg of 1 × 200 mg (880200P-200mg)
pkg of 1 × 25 mg (880200P-25mg)
pkg of 1 × 500 mg (880200P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880200P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC([(OCH2CH2)113OCH3])=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

General description

16:0 PEG5000 PE, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 (DPPE-PEG 5000), is a mPEG phospholipid conjugate. Poly(ethylene glycol) (PEG)-based liposomal formulations are widely used in preparation of biocompatible self-assembled drug-delivery systems. These systems have an ability to escape the recognition and uptake by cells in the immune system at the same time it extends the residence time of the liposomes and allows continuous drug release into the targeted cells.

Application

16:0 PEG5000 PE or 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 has been used in preparation of lipid bilayer. It has also been used in liposome preparation.

Packaging

20 mL Clear Glass Screw Cap Vial (880200P-1g)
20 mL Clear Glass Screw Cap Vial (880200P-500mg)
5 mL Amber Glass Screw Cap Vial (880200P-200mg)
5 mL Amber Glass Screw Cap Vial (880200P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A R Nicholas et al.
Biochimica et biophysica acta, 1463(1), 167-178 (2000-01-13)
Liposomes have been prepared by the vesicle extrusion method (VETs) from mixtures of dipalmitoylphosphatidylcholine (DPPC), phosphatidylinositol (PI) and dipalmitoylphosphatidylethanolamine with covalently linked poly(ethylene glycol) molecular mass 5000 and 2000 (DPPE-PEG 5000 and DPPE-PEG 2000) covering a range of 0-7.5 mole%.
Samantha A Meenach et al.
International journal of nanomedicine, 8, 275-293 (2013-01-29)
Novel advanced spray-dried and co-spray-dried inhalable lung surfactant-mimic phospholipid and poly(ethylene glycol) (PEG)ylated lipopolymers as microparticulate/nanoparticulate dry powders of biodegradable biocompatible lipopolymers were rationally formulated via an organic solution advanced spray-drying process in closed mode using various phospholipid formulations and
Esra Ilhan-Ayisigi et al.
Macromolecular bioscience, 20(6), e2000084-e2000084 (2020-04-30)
In this study, the neoplastic drug frequently used in the treatment of lung cancer, carboplatin is loaded to microbubbles via a microfluidic platform. In order to increase the drug loading capacity of microbubbles, carboplatin is encapsulated into alginate polymer layer.
Mark J Richards et al.
Langmuir : the ACS journal of surfaces and colloids, 33(5), 1285-1294 (2017-01-18)
The supported lipid bilayer has been portrayed as a useful model of the cell membrane compatible with many biophysical tools and techniques that demonstrate its appeal in learning about the basic features of the plasma membrane. However, some of its
David Garenne et al.
Biomacromolecules, 21(7), 2808-2817 (2020-05-23)
Building genetically programmed synthetic cell systems by molecular integration is a powerful and effective approach to capture the synergies between biomolecules when they are put together. In this work, we characterized quantitatively the effects of molecular crowding on gene expression

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