860669P
Avanti
Sphingosine (d16:1)
Avanti Research™ - A Croda Brand 860669P, powder
Synonym(s):
D-erythro-Sphingosine (C16 base)
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About This Item
Empirical Formula (Hill Notation):
C16H33NO2
Molecular Weight:
271.44
UNSPSC Code:
12352211
NACRES:
NA.25
form
powder
packaging
pkg of 1 × 10 mg (860669P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860669P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(N)[C@]([H])(O)/C=C/CCCCCCCCCCC
General description
Sphingosine (d16:1), also known as hexadecasphingosine or hexadecasphing-4-enine, is a minor sphingoid base with 16 carbon atoms. It is one of the major sphingoid bases found in Musca domestica larvae and adults.
Biochem/physiol Actions
Sphingosine is implicated in negative regulation of cell proliferation and stimulation of apoptosis. It has a potential to control the activities of phospholipases, protein kinases, ion channels, cannabinoid receptor type 1 (CB-1) receptors and steroidogenic factor 1 (SF-1) receptors.
Packaging
5 mL Amber Glass Screw Cap Vial (860669P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
No data available
Flash Point(C)
No data available
Certificates of Analysis (COA)
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Ceramides and cerebrosides
Metabolism in the Nervous System, 179-199 (1983)
the
Lipid Mediators and Their Metabolism in the Brain (2011)
The occurrence of tetradecasphing-4-enine and hexadecasphing-4-enine as the principal sphingosines of Musca domestica larvae and adults.
L L Bieber et al.
Biochimica et biophysica acta, 187(1), 157-159 (1969-07-29)
Olivier Cuvillier
Biochimica et biophysica acta, 1585(2-3), 153-162 (2003-01-18)
The sphingolipid metabolites ceramide, sphingosine, and sphingosine 1-phosphate contribute to controlling cell proliferation and apoptosis. Ceramide and its catabolite sphingosine act as negative regulators of cell proliferation and promote apoptosis. Conversely, sphingosine 1-phosphate, formed by phosphorylation of sphingosine by a
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