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810153C

Avanti

16:0-06:0 NBD PE

Avanti Research™ - A Croda Brand 810153C

Synonym(s):

1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoethanolamine

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About This Item

Empirical Formula (Hill Notation):
C33H56N5O11P
CAS Number:
106918-69-8
Molecular Weight:
729.80
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810153C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810153C

concentration

1 mg/mL (810153C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescent probe which contains NBD attached to the headgroup of phosphatidylethanolamine and localized at the membrane interface. Phosphoethanolamine is the second most abundant, metabolically related aminophospholipid. It is mostly enriched in brain.

Application

16:0-06:0 NBD PE is suitable for the determination of enzyme substrate specificity of lipoteichoic acid synthase (LtaS).

Biochem/physiol Actions

Phosphoethanolamine (PE) acts as a substrate for several phospholipids of the cell membrane. N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) aids in monitoring the Red edge excitation shift (REES) effects with its unique motional and dielectric properties.

Packaging

5 mL Amber Glass Screw Cap Vial (810153C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Application of NBD-labeled lipids in membrane and cell biology
Fluorescent methods to study biological membranes, 37-50 (2012)
Jean E Vance et al.
Biochimica et biophysica acta, 1831(3), 543-554 (2012-09-11)
Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are metabolically related membrane aminophospholipids. In mammalian cells, PS is required for targeting and function of several intracellular signaling proteins. Moreover, PS is asymmetrically distributed in the plasma membrane. Although PS is highly enriched in
S C Lopes et al.
Biochimica et biophysica acta. Biomembranes, 1861(6), 1152-1161 (2019-03-07)
Mitochondrial membranes are pointed out as the site of cardiotoxic action of local anaesthetics. Its three main phospholipids components are phosphatidylcholine, phosphatidylethanolamine and cardiolipin. Cardiolipins, in eukaryotes, are only found in mitochondria and are essential for the maintenance of its
Maria Mercedes Palomino et al.
Microbiology (Reading, England), 159(Pt 11), 2416-2426 (2013-09-10)
The probiotic Gram-positive bacterium Lactobacillus casei BL23 is naturally confronted with salt-stress habitats. It has been previously reported that growth in high-salt medium, containing 0.8 M NaCl, leads to modifications in the cell envelope of this bacterium. In this study
Adilson Kleber Ferreira et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 67(6), 481-487 (2013-06-19)
Phosphoethanolamine (Pho-s) is a compound involved in phospholipid turnover, acting as a substrate for many phospholipids of the cell membranes. In a recent study, we showed that Pho-s has antitumor effect in the several tumor cells. In this study we
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