384127
Diphenyl ditelluride
98%
Synonym(s):
Phenyl ditelluride
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About This Item
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Quality Level
Assay
98%
form
powder
mp
65-67 °C (lit.)
SMILES string
[Te]([Te]c1ccccc1)c2ccccc2
InChI
1S/C12H10Te2/c1-3-7-11(8-4-1)13-14-12-9-5-2-6-10-12/h1-10H
InChI key
VRLFOXMNTSYGMX-UHFFFAOYSA-N
Related Categories
General description
Diphenyl ditelluride (PhTe)2 is a versatile reagent used in the organic synthesis. Neurotoxicity by (PhTe)2 depends on the modulation of signaling pathways initiated at the plasma membrane. Comparative toxicological effects of diphenyl diselenide and (PhTe)2 in mice after in vivo administration has been reported. Teratogenic effects of (PhTe)2 on chicken embryo development has been investigated. The oxidative addition of (PhTe)2 to [Pd(PPh3)4] in dichloromethane is reported to yield [Pd6Cl2Te4(TePh)2(PPh3)6]·1/2CH2Cl2.
Application
Diphenyl ditelluride may be used in the assay of organolithium and Grignard reagents.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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PeerJ, 2, e290-e290 (2014-04-09)
Organoselenium compounds have been pointed out as therapeutic agents. In contrast, the potential therapeutic aspects of tellurides have not yet been demonstrated. The present study evaluated the comparative toxicological effects of diphenyl diselenide (PhSe)2 and diphenyl ditelluride (PhTe)2 in mice
The oxidative addition of diphenyl diselenide and ditelluride to tetrakis (triphenylphosphine) palladium.
Journal of Organometallic Chemistry, 623(1), 168-175 (2001)
The Journal of Organic Chemistry, 54, 5627-5627 (1989)
Toxicology mechanisms and methods, 23(9), 660-664 (2013-08-15)
Studies of our group has demonstrated that (PhSe)2 plays some pharmacologic activities. In addition, it is possible that this compound would be an alternative source of organic selenium in animal foods. However, previous works showed that diphenyl diselenide (PhSe)2 and
Toxicology mechanisms and methods, 24(8), 529-535 (2014-05-28)
Diphenyl ditelluride (PhTe)₂ is a versatile molecule used in the organic synthesis and it is a potential prototype for the development of novel biologically active molecules. The mechanism(s) involved in (PhTe)₂ toxicity is(are) elusive, but thiol oxidation of critical proteins
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