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152102

Sigma-Aldrich

Isocarbostyril

98%

Synonym(s):

1(2H)-Isoquinolinone, 1-Hydroxyisoquinoline, 1-Isoquinolinol

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About This Item

Empirical Formula (Hill Notation):
C9H7NO
CAS Number:
491-30-5
Molecular Weight:
145.16
Beilstein:
2954
EC Number:
207-732-1
MDL number:
MFCD00006899
UNSPSC Code:
12352100
PubChem Substance ID:
24849199
NACRES:
NA.22

Assay

98%

form

solid

mp

211-214 °C (lit.)

SMILES string

Oc1nccc2ccccc12.O=C3NC=Cc4ccccc34

InChI

1S/C9H7NO/c11-9-8-4-2-1-3-7(8)5-6-10-9/h1-6H,(H,10,11)

InChI key

VDBNYAPERZTOOF-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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E Naimi et al.
Nucleosides, nucleotides & nucleic acids, 20(8), 1533-1553 (2001-09-14)
A group of unnatural 1-(2-deoxy-beta-D-ribofuranosyl)isocarbostyrils having a variety of C-7 substituents [H, 4,7-(NO2)2, I, CF3, CN, (E)-CH=CH-I, -C triple bond CH, -C triple bond C-I, -C triple bond C-Br, -C=C-Me], designed as nucleoside mimics, were synthesized for evaluation as anticancer
N K Richards et al.
Canadian journal of microbiology, 40(7), 561-566 (1994-07-01)
To facilitate the cloning of DNA encoding isoquinoline degradation an assay was developed that allowed the rapid visual scoring of the isoquinoline degradation phenotype of single colonies. Transposon mutagenesis of one of the isolates. Comamonas acidovorans IQ3, was performed using
Luca Palazzo et al.
Open biology, 9(4), 190041-190041 (2019-04-18)
ADP-ribosylation (ADPr) is a reversible post-translational modification of proteins, which controls major cellular and biological processes, including DNA damage repair, cell proliferation and differentiation, metabolism, stress and immune responses. In order to maintain the cellular homeostasis, diverse ADP-ribosyl transferases and
Tarun Belwal et al.
Frontiers in pharmacology, 11, 41-41 (2020-03-07)
The incidences of diabetic mellitus and other metabolic diseases such as hypertension and hyperlipidemia are increasing worldwide; however, the current treatment is not able to control the rapidly increasing trend in diabetes mortality and morbidity. Studies related to the effectiveness
R Erra-Balsells et al.
Carbohydrate research, 329(1), 157-167 (2000-11-22)
Matrix-assisted ultraviolet laser-desorption ionization time-of-flight mass spectrometry (UV-MALDI-TOF-MS) was applied to sulfated xylo-mannan fractions from Nothogenia fastigiata in order to determine their molecular weights and distribution profiles. The number-average molecular weight calculated from the spectra was similar to that determined
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