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Sigma-Aldrich

N,N-Diethyltrimethylsilylamine

97%

Synonym(s):

(Diethylamino)trimethylsilane, N-(Trimethylsilyl)diethylamine, TMSDEA

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About This Item

Linear Formula:
(C2H5)2NSi(CH3)3
CAS Number:
Molecular Weight:
145.32
Beilstein:
635718
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

vapor density

>1 (vs air)

Quality Level

Assay

97%

form

liquid

refractive index

n20/D 1.411 (lit.)

bp

125-126 °C (lit.)

density

0.767 g/mL at 25 °C (lit.)

SMILES string

CCN(CC)[Si](C)(C)C

InChI

1S/C7H19NSi/c1-6-8(7-2)9(3,4)5/h6-7H2,1-5H3

InChI key

JOOMLFKONHCLCJ-UHFFFAOYSA-N

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General description

N,N-Diethyltrimethylsilylamine is a silylating agent used to derivatize polar organic compounds.

Pictograms

FlameCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Flam. Liq. 2 - Skin Corr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

48.2 °F - closed cup

Flash Point(C)

9 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Said Kinani et al.
Journal of chromatography. A, 1190(1-2), 307-315 (2008-04-09)
This study compares different silylation procedures of zearalenone and its metabolites: alpha-zearalenol, beta-zearalenol, zearalanone, alpha-zearalanol and beta-zearalanol for gas chromatography-mass spectrometry (GC-MS) analysis. Four silylating agents among the most frequently used to derivatize polar organic compounds were tested: N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA)
Sujatha Chilakala et al.
Analytical biochemistry, 566, 62-66 (2018-11-13)
A method is proposed in this paper for the determination of oxygen-18 labeled phosphate so that positional isotope experiments using sensitive and rapid liquid chromatography-QTOF-mass spectrometry (LC-QTOF-MS) experiments can be carried out. The positional isotope exchange technique is a useful

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