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SMB01039

Sigma-Aldrich

Murrayafoline A

≥90% (LC/MS-ELSD)

Synonym(s):

1-Methoxy-3-methyl-9H-carbazole

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About This Item

Empirical Formula (Hill Notation):
C14H13NO
CAS Number:
4532-33-6
Molecular Weight:
211.26
MDL number:
MFCD18452402
UNSPSC Code:
12352205
NACRES:
NA.25

biological source

plant

Assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

211.26

solubility

water: slightly soluble

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

InChI

1S/C14H13NO/c1-9-7-11-10-5-3-4-6-12(10)15-14(11)13(8-9)16-2/h3-8,15H,1-2H3

InChI key

HDETUOZJFUNSKG-UHFFFAOYSA-N

General description

Murrayafoline A, a carbazole alkaloid, is a bioactive natural compound commonly derived from plants such as Murraya euchrestifolia, Murraya kwangsiensis, Clausena excavata, Clausena dunniana, and Glycosmis stenocarpa. Current research indicates that this plant metabolite is an inhibitor and may possess diverse biological activities, including anticancer, antimalarial, cardioprotective and antifungal properties.

Application

Murrayafoline A is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Murrayafoline A may be a potential chemotherapeutic agent for use in the treatment of colon cancer and may be useful in preventing the progression of vascular complications such as restenosis.

Features and Benefits

  • Suitable for Biochemical and Biomedical research
  • Versatile and adaptable for wide variety of laboratory and research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H341,H351,H413

Hazard Classifications

Aquatic Chronic 4 - Carc. 2 - Muta. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Joo-Hui Han et al.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 19(5), 421-426 (2015-09-04)
The increased potential for vascular smooth muscle cell (VSMC) growth is a key abnormality in the development of atherosclerosis and post-angioplasty restenosis. Abnormally high activity of platelet-derived growth factor (PDGF) is believed to play a central role in the etiology
Hyuk Choi et al.
Biochemical and biophysical research communications, 391(1), 915-920 (2009-12-08)
Molecular lesions in Wnt/beta-catenin signaling and subsequent up-regulation of beta-catenin response transcription (CRT) occur frequently during the development of colon cancer. To identify small molecules that suppress CRT, we screened natural compounds in a cell-based assay for detection of TOPFalsh

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