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S9991

Sigma-Aldrich

Recombinant SARS-CoV-2 nucleocapsid protein

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.26
Pricing and availability is not currently available.

form

frozen liquid

Quality Level

200

storage condition

avoid repeated freeze/thaw cycles

technique(s)

ELISA: suitable
lateral flow assay: suitable

storage temp.

−70°C

General description

This Nucleoprotein (nucleocapsid protein) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is expressed in insect cells. The Nucleocapsid protein is not important for determination of neutralizing IgG antibodies. However, the recombinant SARS-CoV-2 Nucleocapsid Protein, S9991 antigen in combination with monoclonal antibodies directed against neutralizing epitopes such as the ACE2 binding domain could be used in a competitive setup for determining neutralizing antibodies. The nucleocapsid protein is quite conserved. Using nucleocapsid protein for acute / early antibodies such as IgA/ IgM should make it possible to detect antibodies directed against the variants of concern in a satisfactory way at an early stage of illness.
For IgM detection, a mixture of nucleocapsid and spike proteins is recommended.

Physical form

sab5700595

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

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Certificates of Analysis (COA)

Lot/Batch Number
SLCK2510

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Questions

  1. Can you provide the amino acid sequence for the Recombinant SARS-CoV-2 nucleocapsid protein with item number S9991?

    1 answer

    1. The SARS-CoV-2 Nucleoprotein, BM6424, contains the full-length sequence (aa1-419) of SARS-CoV-2 Nucleoprotein (GenBank: QHD43423.2) and is fused at the C-terminus to a Streptag. This product is an isolate of "Wuhan-Hu-1".

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