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O6254

Sigma-Aldrich

(R)-(−)-2-Oxothiazolidine-4-carboxylic acid

≥98% (titration), suitable for plant cell culture

Synonym(s):

L-(−)-2-Oxothiazolidine-4-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C4H5NO3S
CAS Number:
19771-63-2
Molecular Weight:
147.15
Beilstein:
4179169
MDL number:
MFCD00066092
UNSPSC Code:
12352106
PubChem Substance ID:
24898032
NACRES:
NA.26

product name

(R)-(−)-2-Oxothiazolidine-4-carboxylic acid, ≥97% (TLC), ≥98% (titration)

Quality Level

200

Assay

≥97% (TLC)
≥98% (titration)

form

(powder to crystals)

technique(s)

cell culture | plant: suitable

color

white to off-white

SMILES string

OC(=O)[C@@H]1CSC(=O)N1

InChI

1S/C4H5NO3S/c6-3(7)2-1-9-4(8)5-2/h2H,1H2,(H,5,8)(H,6,7)/t2-/m0/s1

InChI key

BMLMGCPTLHPWPY-REOHCLBHSA-N

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Application


  • Artificial elevation of glutathione contents in salicylic acid-deficient tobacco (Nicotiana tabacum cv. Xanthi NahG) reduces susceptibility to the powdery mildew pathogen Euoidium longipes.: This study explores the impact of enhanced glutathione levels on resistance to powdery mildew in tobacco plants deficient in salicylic acid, indicating a potential application of R-(−)-2-Oxothiazolidine-4-carboxylic acid in managing plant diseases (Künstler et al., 2020).

Biochem/physiol Actions

2-Oxothiazolidine-4-carboxylic acid augments glutathione and cysteine production.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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A Künstler et al.
Plant biology (Stuttgart, Germany), 22(1), 70-80 (2019-07-10)
The effects of elevated glutathione levels on defence responses to powdery mildew (Euoidium longipes) were investigated in a salicylic acid-deficient tobacco (Nicotiana tabacum cv. Xanthi NahG) and wild-type cv. Xanthi plants, where salicylic acid (SA) contents are normal. Aqueous solutions
María José Clemente-Moreno et al.
Plant, cell & environment, 36(3), 640-654 (2012-08-24)
Sharka, a disease caused by plum pox virus (PPV), has a significant economic impact on fruit tree production. In this work, we analysed the effect of (2,1,3)-benzothiadiazole (BTH) and L-2-oxo-4-thiazolidine-carboxylic acid (OTC) on plant growth and virus content. OTC reduced
T-H Lee et al.
International endodontic journal, 43(5), 430-435 (2010-06-04)
To evaluate the mechanisms of cytotoxicity of chlorhexidine (CHX) in human osteoblastic cells in vitro. Cytotoxicity, cell proliferation and collagen synthesis assays were performed to elucidate the toxic effects of CHX on the human osteoblastic cell line U2OS. To determine
Anna Vávrová et al.
Archives of toxicology, 85(5), 525-535 (2010-11-04)
The clinical usefulness of anthracycline antineoplastic drugs is limited by their cardiotoxicity. Its mechanisms have not been fully understood, although the induction of oxidative stress is widely believed to play the principal role. Glutathione is the dominant cellular antioxidant, while
Jeffrey S Otis et al.
Alcohol and alcoholism (Oxford, Oxfordshire), 45(6), 495-500 (2010-10-12)
To assess the effectiveness of procysteine (PRO) supplementation provided during a period of abstinence (ABS) on alcohol-induced skeletal muscle atrophy and oxidant stress. Age- and gender-matched Sprague-Dawley rats were fed the Lieber-DeCarli liquid diet containing either alcohol or an isocaloric
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