when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.
Application
Epoxy-activated-Sepharose™ is used in affinity chromatography, protein chromatography, and activated/functionalized matrices. Epoxy-activated-Sepharose™ has been used to obtain a monoclonal antibody against the prokaryotically expressed foot-and-mouth disease virus (FMDV) non-structural protein (NSP) 3B as well as to study B meningococcal disease.
Other Notes
Ligand: 1,4-bis(2:3-Epoxypropoxy)butane Attachment: one epoxy group Spacer: provides a 12-atom spacer when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.
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