Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

A5686

Sigma-Aldrich

Arg-Gly-Glu-Ser acetate salt

≥95% (HPLC)

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C16H29N7O8
CAS Number:
159002-32-1
Molecular Weight:
447.44
MDL number:
MFCD00133106
UNSPSC Code:
12352202
PubChem Substance ID:
329770831
NACRES:
NA.32
Pricing and availability is not currently available.

biological source

synthetic (organic)

Assay

≥95% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

CC(O)=O.N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(O)=O

InChI

1S/C16H29N7O8.C2H4O2/c17-8(2-1-5-20-16(18)19)13(28)21-6-11(25)22-9(3-4-12(26)27)14(29)23-10(7-24)15(30)31;1-2(3)4/h8-10,24H,1-7,17H2,(H,21,28)(H,22,25)(H,23,29)(H,26,27)(H,30,31)(H4,18,19,20);1H3,(H,3,4)/t8-,9-,10-;/m0./s1

InChI key

SALKOFBHHIHLSW-PUBMXKGKSA-N

Gene Information

human ... FN1(2335)
mouse ... FN1(14268)
rat ... FN1(25661)

Amino Acid Sequence

Arg-Gly-Glu-Ser

Application

Arg-Gly-Glu-Ser acetate salt has been used:
  • as an integrin blocking peptide to study its effects on ciliary neurotrophic factor (CNTF) regulation in astroglioma cells[1]
  • as a control peptide to study its effects on the binding of patient IgG to integrin αvβ6[2]
  • as an integrin inhibitor peptide to study its effects on cell adhesion in Capsaspora owczarzaki cells[3]

Biochem/physiol Actions

Arg-Gly-Glu-Ser peptide acts as an integrin-blocking peptide.[1]
Inhibitor of platelet aggregation

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SLCJ5343
SLCH5094
SLCC1664
SLBW8777
SLBW5172

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Helena Parra-Acero et al.
Current biology : CB, 30(21), 4270-4275 (2020-08-29)
In animals, cell-matrix adhesions are essential for cell migration, tissue organization, and differentiation, which have central roles in embryonic development [1-6]. Integrins are the major cell surface adhesion receptors mediating cell-matrix adhesion in animals. They are heterodimeric transmembrane proteins that
Seong Su Kang et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(27), 9277-9287 (2012-07-06)
Ciliary neurotrophic factor (CNTF) is a potent neural cytokine with very low expression in the CNS, predominantly by astrocytes. CNTF increases rapidly and greatly following traumatic or ischemic injury. Understanding the underlying mechanisms would help to design pharmacological treatments to
Gartner, T.K., et al.
Blood, 66, 305a-305a (1985)
Hiroyuki Yoshida et al.
Journal of gastroenterology, 58(8), 778-789 (2023-06-13)
Patients with primary sclerosing cholangitis (PSC) possess autoantibodies against biliary epithelial cells. However, the target molecules remain unknown. The sera of patients with PSC and controls were subjected to enzyme-linked immunosorbent assays to detect autoantibodies using recombinant integrin proteins. Integrin
Jose V Moyano et al.
Molecular biology of the cell, 21(21), 3654-3668 (2010-09-17)
Laminin (LM)-332 is an extracellular matrix protein that plays a structural role in normal tissues and is also important in facilitating recovery of epithelia from injury. We have shown that expression of LM-332 is up-regulated during renal epithelial regeneration after
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service